Four (2-phenol derivatives) were coupled with 1H-tetrazole-5-diazonium chloride to synthesize four new compounds namely Ta-d. These prepared Azophenols reacted with two 4-alkoxy acids (8 and 10) to form two new series of 4-((1H-tetrazol-5-yl) diazenyl)-2-(R)-phenyl-4-(octyloxy) benzoates T8a-d and 4-((1H-tetrazol-5-yl)diazenyl)-2-(R)-phenyl-4-(decyloxy) benzoates T10a-d respectively. The structures of the twelve synthesized compounds were confirmed using the conventional tools of analysis, Elemental Analysis, FT-IR and 1H-NMR spectroscopy. They were tested as anti-fungi and anti-bacteria. Most of the prepared compounds possessed good antimicrobial action for Gram Positive and Gram-Negative Bacteria, whereas they gave no action on Aspergillus Fumigatus or Candida albicans.
Nessim, M., Elewa, S. I., & Mohamed, M. G. (2018). Synthesis and Study Antimicrobial Activities of Some Novel Tetrazole Derivatives. Egyptian Journal of Chemistry, 61(1), 197-206. doi: 10.21608/ejchem.2018.2214.1178
MLA
Maher Nessim; Safaa I. Elewa; Manal G. Mohamed. "Synthesis and Study Antimicrobial Activities of Some Novel Tetrazole Derivatives". Egyptian Journal of Chemistry, 61, 1, 2018, 197-206. doi: 10.21608/ejchem.2018.2214.1178
HARVARD
Nessim, M., Elewa, S. I., Mohamed, M. G. (2018). 'Synthesis and Study Antimicrobial Activities of Some Novel Tetrazole Derivatives', Egyptian Journal of Chemistry, 61(1), pp. 197-206. doi: 10.21608/ejchem.2018.2214.1178
VANCOUVER
Nessim, M., Elewa, S. I., Mohamed, M. G. Synthesis and Study Antimicrobial Activities of Some Novel Tetrazole Derivatives. Egyptian Journal of Chemistry, 2018; 61(1): 197-206. doi: 10.21608/ejchem.2018.2214.1178
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