Severe Bleeding in Preoperative Conditions: Emergent Interventions to Control Condition-An Updated Review

Document Type : Review Articles

Authors

1 First Riyadh Health Cluster, Ministry of Health, Saudi Arabia

2 King Saud Medical City, Saudi Arabia

Abstract

Background: Severe bleeding during preoperative and intraoperative conditions remains a major cause of morbidity and mortality. The risk of hemorrhage is heightened by factors such as trauma, anticoagulant therapies, and surgical complications. Effective preoperative management and timely interventions are crucial for controlling severe blood loss and minimizing the associated risks.
Aim: This review aims to provide an updated synthesis of interventions and strategies used to control severe bleeding in preoperative conditions, focusing on the mechanisms of hemorrhage, risk factors, and the management techniques employed to stabilize patients.
Methods: A comprehensive review of the existing literature was conducted, analyzing the underlying mechanisms of bleeding, including coagulopathy and the body's response to hemorrhagic shock. Clinical approaches such as fluid resuscitation, pharmaceutical interventions, and surgical techniques for managing severe bleeding were discussed.
Results: The review highlighted that hemorrhagic shock often occurs due to trauma-induced coagulopathy, shock, or the consumption of clotting factors. Fluid resuscitation strategies, including the use of crystalloids, colloids, and blood products, are essential in stabilizing patients. Additionally, medications such as inotropes and adrenergic agonists play a vital role in improving cardiac output and blood pressure. Effective interventions in managing hemorrhagic shock were found to rely heavily on rapid response, tailored treatments, and evidence-based guidelines.
Conclusion: Severe bleeding in preoperative conditions presents a complex challenge. Immediate intervention through appropriate fluid therapy, the use of pharmaceuticals, and surgical techniques are essential in controlling blood loss. The timely recognition and management of coagulopathy, hemorrhagic shock, and underlying health conditions are critical to improving patient outcomes and reducing mortality in these high-risk situations.

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Egyptian Journal of Chemistry
Volume 67, Issue 13 - Serial Number 13
In Loving Memory of Late Professor Doctor ””Mohamed Refaat Hussein Mahran””
December 2024
Pages 1803-1811

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History

  • Receive Date: 23 December 2024
  • Revise Date: 29 December 2024
  • Accept Date: 31 December 2024

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