Investigation of the biological activity of silver nanoparticles biosynthesized from Echinops ritro L

Document Type : Original Article

Authors

1 Département of pharmacy, faculty of medecine, Ahmed Ben Bella university, Oran1. Algeria.

2 Phytochemistry & Organic Synthesis Laboratory,Tahri Mohamed university .Bechar .Algeria

3 Faculty of natural sciences and life, Tahri Mohamed university, Bechar.Algeria

4 Laboratory of Energetic in Arid Zones, solar fields team and its applications, Faculty of Exact Sciences, department of matter sciences, university of Tahri Mohammed Bechar. Algeria

Abstract

The biosynthesis of silver nanoparticles (AgNPs) is the subject of this investigation using the ethanolic extract of Echinops ritro L., a medicinal plant from the Asteraceae family, and evaluates their antimicrobial properties. A combination of spectroscopic methods was used to characterise the biosynthesised AgNPs. The UV-visible spectrum showed a characteristic absorption band at 415 nm, confirming AgNPs formation investigation revealed several functional groups that contribute to the stabilisation and reduction of AgNPs. XRD confirmed the crystalline nature of the nanoparticles with an average size of 23.36 nm. The antimicrobial activity of the synthesized AgNPs was assessed against five bacterial strains (Escherichia coli, Enterococcus faecalis, Proteus mirabilis, Enterococcus hirae, and Bacillus cereus) and one fungal species (Candida albicans) using the disc diffusion method. The AgNPs exhibited significant antibacterial activity, with inhibition zones ranging from 5 to 33 mm, depending on the concentration and bacterial strain tested. The E. coli bacteria showed the strongest antibacterial activity, with an inhibitory zone measuring 33±12.5 mm at a concentration of 100 μg/mL. The AgNPs also demonstrated antifungal activity against C. albicans, with a maximum inhibition zone of 21± mm at 100 μg/mL. This research highlights the potential of Echinops ritro L. extract for the green synthesis of AgNPs with promising antimicrobial properties, offering a sustainable approach for developing new antimicrobial agents.

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Egyptian Journal of Chemistry
Volume 67, Issue 13 - Serial Number 13
In Loving Memory of Late Professor Doctor ””Mohamed Refaat Hussein Mahran””
December 2024
Pages 1621-1629

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History

  • Receive Date: 23 August 2024
  • Revise Date: 16 October 2024
  • Accept Date: 19 November 2024

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