Authentication of Cherry (Muntingia calabura) Fruit from different Geographical Locations in Indonesia by FTIR Spectroscopy Combined with Chemometrics and Their Antioxidant and Antiaging Activities

Document Type : Original Article

Authors

1 Department of Pharmaceutical Chemistry, Sekolah Tinggi Ilmu Farmasi Makassar

2 Department of Pharmaceutical Technology, Sekolah Tinggi Ilmu Farmasi Makassar

3 Sekolah tinggi ilmu farmasi makassar

Abstract

Cherry (Muntingia calabura L) is a plant with scientific properties in various treatments. Cherry can overgrow in a variety of environments. This study aims to determine the similarity profile of the compound content of cherries obtained at different geographical locations using the FT-IR-chemometric spectroscopy approach and their bioactivity as antioxidants and anti-aging. Cherry fruit obtained from 8 regions in South Sulawesi Province-Indonesia was dried and extracted using the sonicator method for 30 minutes. The extract obtained was analyzed by FT-IR spectroscopy and authenticated by the chemometric similarity of the compounds (PCA and Cluster analysis). The test results showed that the ethanol extract of cherry fruit from various regions had a similarity of 65.4% and, by dendogram, tended to form 2 clusters based on the profile of chemical content and intensity. Antioxidant activity profiles using DPPH and ABTS methods showed that bioactivity varied from strong to powerful. The same thing was also found in the anti-elastase activity showing variations based on a percentage of elastase inhibition and the IC50 value. But overall, the various test results did not significantly affect the bioactivity of cherry fruit as an antioxidant and anti-aging.

Keywords

Egyptian Journal of Chemistry
Volume 66, Issue 13 - Serial Number 13
Special Issue: Applied Chemistry for Greener Life and Sustainability
December 2023
Pages 2379-2388

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History

  • Receive Date: 11 October 2022
  • Revise Date: 12 November 2022
  • Accept Date: 30 November 2022

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