Determination of Ferrous Ion in Pure & Pharmaceutical Preparation by Continuous Flow Injection Analysis Via Turbidmetric Utilizing NAG-4SX3-3D Analyzer

Document Type : Original Article

Authors

1 Department of chemistry, College of science, University of Baghdad, Baghdad, Iraq

2 Chemistry, Faculty of Science, University of Baghdad, Baghdad, Iraq

Abstract

A simple and efficient established method that is characterized by its quickness and high sensitivity for determining ferrous ion in pure and pharmaceutical formulations by the generate of dark-blue precipitate using reaction of hexacyanoferrate(III) with ferrous ion in ammonium acetate medium. The equipment NAG-4SX3-3D analyzer was used to quantify turbidity by measuring the incident light attenuation crashing on the precipitate surface granules (0-180 degree). The optimum parameter has been investigated in order to improve the newly created approach's sensitivity.

The linear range (0.1-7) millimol.L-1 with (r=0.9971), (correlation coefficient), percentage linearity (R % = 99.42), and RSD % for the repetition (n=7) also were lower than 0.1 percent for the measurement of ferrous ion, with concentration (1, 4.7 millimol .L-1). Whereas L.O.D. = 212.6712 ng/sample from the progressive dilution throughout the calibration graph's lowest concentration linear dynamic range the suggested approach was compared to the traditional method (UV- spectrophotometric at λmax = 222 nm of analysis employing the conventional technique of adding by the use of paired t- test (the mean difference between pairs of measurements). It’s notice that with calculated numbers, there wasn't any substantial variation between the values given of any particular firm. t-value at 95% interval from the proposed approach.

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Egyptian Journal of Chemistry
Volume 65, Issue 131 - Serial Number 13
Special Issue: Chemistry and Global Challenges (Part A)
December 2022
Pages 871-886

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History

  • Receive Date: 03 April 2022
  • Revise Date: 30 April 2022
  • Accept Date: 17 May 2022

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