Green Synthesis of Gold Nanoparticles Reduced and Stabilized By Carboxyethyl Chitosan for Viscose Fabric Finishing

Document Type : Original Article


1 High institute of applied arts, the 5thP District, Cairo, Egypt

2 Solid State Physics department, Institute of Physics Research, National Research Centre, 33 El Bohouth st., Dokki, Cairo, Egypt, P.O.12622


A green chemistry methodological approach was used in the preparation of nanostructures, which is a result of incredible and innovative medical applications. Polysaccharides were utilized as a reducing and stabilizing agent in the synthesis of gold nanoparticles (AuNPs). We used carboxyethyl chitosan (CECS) as a reducing agent and a gold nanoparticle as a capping agent in this study. CECS is made by reacting chitosan with acrylic acid in an alkaline media, as described previously. At 100 oC for 1 hour, AuNPs were made with varied concentrations of carboxyethyl chitosan (0.2 percent w/v, 0.5 percent w/v, and 1 percent w/v). The nitrogen content, carboxyl content, and FTIR spectra were used to characterize CMCS. UV spectrophotometry and TEM images were used to identify AuNPs. Finally, the cytotoxicity of the produced AuNPs was assessed using an MMT assay for cell viability and IC50 values in comparison to AuNPs synthesized via chemical techniques. The results reveal that AuNPs have a normal distribution with 15-25 nm particle size and that their cytotoxicity is reduced when made using this green approach, indicating that GNPs can be used safely in skin contact medical therapy


Main Subjects

Volume 65, Issue 131 - Serial Number 13
Special Issue: Chemistry and Global Challenges (Part A)
December 2022
Pages 1-9
  • Receive Date: 20 March 2022
  • Revise Date: 31 March 2022
  • Accept Date: 06 April 2022