An active heterocyclic unite building represented by 1,3,4-Thiadiazole-2,5-dithiole (1) was prepared through the reaction of carbon disulfide and hydrazine hydrate .This unite building was reacted with hydrazine hydrate to afford the corresponding 2,5-dihydrazino -1,3,4-thiadiazole(2)which then undergoes one-pot catalyst-free multicomponent reaction with malononitrile, substituted aldehyde and ethyl acetoacetate to obtained 2,5-di(3-methyl-4-aryl-pyrano[2,3-c]pyrazole-5-amino-6-cyno-1-yl)-1,3,4-thiadiazole (3-9). All prepared compounds were elucidated by available methods represented by M.P,T.L.C,FT-IR and for some compounds 1H.NMR.
Khazaal, S., & Ibraheam, S. (2022). One- Pot Synthesis of New Pyranopyrazoles Via Domino Multicomponent Reaction. Egyptian Journal of Chemistry, 65(10), 259-265. doi: 10.21608/ejchem.2022.115337.5232
MLA
Shaymaa Khazaal; Shaimaa Y. Ibraheam. "One- Pot Synthesis of New Pyranopyrazoles Via Domino Multicomponent Reaction". Egyptian Journal of Chemistry, 65, 10, 2022, 259-265. doi: 10.21608/ejchem.2022.115337.5232
HARVARD
Khazaal, S., Ibraheam, S. (2022). 'One- Pot Synthesis of New Pyranopyrazoles Via Domino Multicomponent Reaction', Egyptian Journal of Chemistry, 65(10), pp. 259-265. doi: 10.21608/ejchem.2022.115337.5232
VANCOUVER
Khazaal, S., Ibraheam, S. One- Pot Synthesis of New Pyranopyrazoles Via Domino Multicomponent Reaction. Egyptian Journal of Chemistry, 2022; 65(10): 259-265. doi: 10.21608/ejchem.2022.115337.5232
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