Synthesis and characterization of nano CuO/ZnO/Al2O3 catalyst via Laser ablation route for the preparation of some cyanoacetanilide derivatives

Sarhan, Ahmed; Abdelghany, Amr M.; El- Dossoki, Farid

doi:10.21608/ejchem.2021.103671.4798

Synthesis and characterization of nano CuO/ZnO/Al2O3 catalyst via Laser ablation route for the preparation of some cyanoacetanilide derivatives

Document Type : Original Article

Authors

¹ Chemistry Department, Faculty of Science, Port Said University, Port Said, Egypt.

² Spectroscopy Department, Physics Research Institute, National Research Centre, 33 Elbehouth St., Dokki 12311, Egypt

³ Basic and Applied Science Department, Horus University, Coastal–Road, New–Damietta, Egypt

10.21608/ejchem.2021.103671.4798

Abstract

As an alternate physical technique, laser ablation is considered a promising and effective route that may be used for the creation of nanoparticles. The main goal of this study is to synthesis CuO/ZnO/Al2O3 nanoparticles in aqueous media using laser ablation route in deionized water (DIW), to be used for the synthesis of 2-cyano-2-( p - nitrobenzylidene)- p -methoxyacetanilide via Knoevenagel condensation reaction between p-nitrobenzaldehyde and 2-cyano-N-(4methoxyphenyl) acetamide compounds. This protocol was used to obtain a high yield of the final product. The method is considered solvent-free, eco-friendly, short-time reaction, and excellent yield in comparison with that using catalyst in the bulk form. The antibacterial properties of the synthesized products were evaluated against Gram-positive (Streptococcus bacteria) and Gram-negative bacteria (Enterococcus bacteria).

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