Synthesis, identification, biological activity and anti-cancer activity Studies of Hetrocyclic Ligand Azo-schiff Base with Au(III) Complex

Document Type : Original Article

Authors

1 department of chemistry, college of science, university of Al Qadisiyah, Iraq

2 University of Al-Qadisiyah, college of Science, chemistry department-Iraq

Abstract

This research involved preparation of 2-((E)-(1H-benzo.[d]imidazol-2-yl).diazenyl)-4-(((4-bromophenyl)imino)methyl)phenol and Au(III) complex which was prepared by mixing solution of metal salt with ligand solution at mole ratio[ M:L] 1:1 . Compounds prepared were identified by FT- IR,, elemental analyses (C.H.N). Molar conductance measurements, magnetic susceptibility UV-Visb. The biological activity of the compounds prepared were examined against the susceptible organisms Streptococcus, (Gram. Positive) and Escherichia coli ,(Gram .negative), as antibacterial and Penicillium. Sp and Aspergillus Niger as antifungal,
The prepared compounds checked for anti-cancer activity; activity of anti-tumor against of breast cancer for human

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History

  • Receive Date: 12 June 2021
  • Revise Date: 07 July 2021
  • Accept Date: 12 July 2021

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