Green Synthesis of Zinc Oxide Nanoparticles Using Portulaca oleracea (Regla Seeds) Extract and Its Biomedical Applications

Mohamed, Hend Y.G.; Ismael, Eman; Elaasser, Mahmoud M.; Khalil, Mostafa M.H.

doi:10.21608/ejchem.2020.45592.2930

Green Synthesis of Zinc Oxide Nanoparticles Using Portulaca oleracea (Regla Seeds) Extract and Its Biomedical Applications

Document Type : Original Article

Authors

¹ Chemistry Department, Faculty of Science, Ain Shams University

² Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, Egypt

³ The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo, Egypt

10.21608/ejchem.2020.45592.2930

Abstract

In the present study, the biosynthesis of ZnONPs utilizing Portulaca oleracea seeds aqueous extract has been reported. The reported method is a green, plant-extract mediated and low-cost approach that is capable of synthesizing ZnONPs at pH 7 with heating at 60 oC for one hour. To demonstrate the efficiency of the capping bioorganic molecules on ZnO nanoparticles, a part of the product was dried at 60 oC (denoted ZnO-60) and the other part was annealed at 500 oC (denoted ZnO-500). Both synthesized ZnONPs was crystalline in nature and hexagonal in shape with an average size of 14 nm and 34.5 nm for ZnO-60 and ZnO-500, respectively, as evidenced by XRD and TEM analysis. The synthesized nanoparticles showed high antioxidant, good antibacterial activity, which has inhibited the growth of Helicobacter pylori (ATCC 700392) and Methicillin-Resistant Staphylococcus aureus bacteria and anticancer activity for HCT-116 cells with a higher efficiency of ZnO-60 than ZnO-500.

Keywords