In vitro Antimicrobial Activity Evaluation of Newly Synthesized Furochromone Schiff Base Complexes

Shakdofa, Mohammed M; Abdel Hady Mousa, Hanan; Labib, Ammar Ahmed; Abd El-All, Amira; Bassyouni, Fatma

doi:10.21608/ejchem.2018.2222.1180

In vitro Antimicrobial Activity Evaluation of Newly Synthesized Furochromone Schiff Base Complexes

Document Type : Original Article

Authors

¹ Department of Inorganic Chemistry, National Research Centre, El-Bohouth St., Dokki, Cairo, Egypt

² Department of Inorganic Chemistry, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cairo, Egypt

³ Inorganic Chemistry Department, National Research Centre, El Behoos St., Dokki, Cairo, Egypt.

⁴ Department of Natural and Microbial Products, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cairo, Egypt

⁵ Department of Natural and Microbial Products, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cai-ro, Egypt

10.21608/ejchem.2018.2222.1180

Abstract

A series of VOII, NiII, CuII, CoII, MnII, CdII and ZnII complexes of new Schiff base ligand resulting form 4-aminoantipyrine and Furobenzopyrone were prepared. The structure of newly synthesized compounds (1-8) was proven by studying their elemental analyses, spectral data (IR, NMR, UV-vis), molar conductivity and magnetic susceptibility. In addition the in vitro antimicrobial activi-ty of all compounds was examined. The results cleared that nickel and zinc complexes exhibited promising activity compared with standard drug (chloramphenicol).

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