Diazenyl Chalcones Incorporating Thiazole moiety: Synthesis, Spectroscopic Characterizations, Dyeing Performance, and Antimicrobial Efficacy

El-Samoly, Mariem M.; Dawoud, Nadia T. A.; El-Fakharany, Esmail M.; Mashaly, Hamada M.; Abbas, Dalia M.; Lotfy, Doaa R.

doi:10.21608/ejchem.2025.415928.12225

Diazenyl Chalcones Incorporating Thiazole moiety: Synthesis, Spectroscopic Characterizations, Dyeing Performance, and Antimicrobial Efficacy

Document Type : Original Article

Authors

¹ Chemistry Department, Faculty of Science, Girls, Al-Azhar University, Nasr City, Cairo, Egypt.

² Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria 21934, Egypt..

³ Textile Research Division, National Research Centre, Dokki, Cairo 12622, Egypt.

⁴ Processes Design & Development Department, Egyptian Petroleum Research Institute, Nasr City, Cairo, Egypt.

10.21608/ejchem.2025.415928.12225

Abstract

Numerous polyfunctionalized heterocyclic compounds containing azo groups have been synthesized utilizing thiazolidine derivatives 1a-e as precursors. Mass, NMR, and infrared spectra are among the spectrum analyses used to verify the structures of the generated molecules. Following the application of a variety of dyestuffs to polyester fabrics, the dyed samples showed suitable levels of light fastness, rubbing, washing, and thermal fixation fastness, as well as highly excellent sweat resistance. Fabrics dyed with the dyestuffs also offer adequate UV protection properties, according to the UPF measurements of the fabric samples 2-3a, b, d, e. The dyed fabric has a higher UPF value (50+). Gram-positive and Gram-negative microorganisms, as well as Candida albicans, were tested for antimicrobial activity in the fabric samples. All evaluated fabrics demonstrated measurable antibacterial efficacy.

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