Because of its importance in medicinal chemistry, scientists have been interested in linking sulfaguanidine to different heterocycles to develop potential bioactive candidates. Four approaches have been adopted to accomplish this. The adopted approaches included condensation with electrophilic reactants, coupling with nucleophilic aromatics and active methylene compounds, click cycloaddition, and multicomponent reaction. This review reports all the adopted synthetic approaches, the biological activities studied, and the mechanistic investigations of the reported organic sulfaguanidine-linked molecules throughout 2015-2024.
Abulkhair, H. (2025). Synthetic approaches, biological activity evaluations, and mechanistic investigations of sulfaguanidine-linked molecules. Egyptian Journal of Chemistry, (), -. doi: 10.21608/ejchem.2025.357091.11242
MLA
Hamada S. Abulkhair. "Synthetic approaches, biological activity evaluations, and mechanistic investigations of sulfaguanidine-linked molecules", Egyptian Journal of Chemistry, , , 2025, -. doi: 10.21608/ejchem.2025.357091.11242
HARVARD
Abulkhair, H. (2025). 'Synthetic approaches, biological activity evaluations, and mechanistic investigations of sulfaguanidine-linked molecules', Egyptian Journal of Chemistry, (), pp. -. doi: 10.21608/ejchem.2025.357091.11242
VANCOUVER
Abulkhair, H. Synthetic approaches, biological activity evaluations, and mechanistic investigations of sulfaguanidine-linked molecules. Egyptian Journal of Chemistry, 2025; (): -. doi: 10.21608/ejchem.2025.357091.11242
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