Biosynthesis of biologically active silver Nano particles using natural red pigment under optimized conditions

Ali Abdulla, I.; Gomaa, Sanna K.; Abd-elsalam, I.S.

doi:10.21608/ejchem.2025.350811.11122

Biosynthesis of biologically active silver Nano particles using natural red pigment under optimized conditions

Articles in Press

Document Type : Original Article

Authors

¹ Department of Botany , Faculty of Science, Sirte University

² Chemistry of Natural and Microbial Products Dept., Pharmaceutical and Drug Research Institute, National Research Center(NRC), Dokki ,Cairo, Egypt

10.21608/ejchem.2025.350811.11122

Abstract

Abstract

The microbial production of natural red pigment was investigated using Penicillium purpurgenium .Optimization of pigment production was carried out under different growth conditions involving different carbon source, fermentation time, pH value as well as addition of some additives. The results revealed that the maximum production of pigment ( 295 mg/L) was obtained by using sucrose conc. (20g/L) , production time 8 days, pH 6 at 30C accompanied by the addition of Mg+2and Mn+2 salts. The separated pigment was used for synthesis of nano-silver particles (AgNPs) , characterization of the obtained nano-particles was carried out and determination of their Antimicrobial activity. TEM images showed that the generated nanoparticles were spherical and , hexagonal shaped with particle size (4-70)nm.

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