Rubus Species: A Natural Treasure Trove of Bioactives and Their Therapeutic Potential

Alharshani, Essam Mobark; Abd El-Kader, Essam Mostafa; Abdelhameed, Mohamed Fayed; Kirolos, Farid; El-Raey, Mohamed A.; El Hawary, Seham

doi:10.21608/ejchem.2025.350063.11098

Rubus Species: A Natural Treasure Trove of Bioactives and Their Therapeutic Potential

Document Type : Review Articles

Authors

¹ Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt

² Plant Tissue Culture Reda. Lab., Hot. Reda. Instit., Afri. Reda. Centr

³ Pharmacology department, medical division, national research centre

⁴ Department of Phytochemistry and Plant Systematics, Pharmaceutical Division, National Research Centre, 33 El-Bohouth St., Dokki, Cairo 12622, Egypt

⁵ Department of Pharmacognosy, Faculty of Pharmacy, Cairo University

10.21608/ejchem.2025.350063.11098

Abstract

The genus Rubus, a prominent member of the Rosaceae family, is well-known for its traditional medicinal uses and has been extensively studied for its diverse array of bioactive compounds. Numerous Rubus species have been the focus of phytochemical and pharmacological research, utilizing both in vivo and in vitro approaches. This review aims to explore the bioactive chemical components of Rubus plants, their therapeutic properties, the mechanisms of action of these compounds, and recent developments in uncovering the potential of lesser-known species. Additionally, it will highlight the value-added products derived from Rubus that contribute to enhancing livelihood stability.

Keywords