Future Treatment of Cancer: Effectiveness of Integra, Herba Extracts, And Chitosan Nano biopolymer Integration in Cancer Therapy (a Narrative Review)

Document Type : Review Articles

Authors

1 Faculty of Natural Sciences, Islamic University of Indonesia

2 Department of Pharmacy, Universitas Islam Indonesia, Yogyakarta, 55584, Indonesia

Abstract

Cancer is a global issue affecting all ages and genders. Chemotherapy, while common, has significant physical and psychological side effects, prompting exploration of traditional herbal treatments. However, herbal products often suffer from poor solubility and bioavailability. To address this, chitosan nanobiopolymers are being investigated for their potential to enhance the effectiveness of herbal extracts. This review aims to assess the integration of chitosan nanobiopolymers with herbal extracts as anticancer agents and their manufacturing process, utilizing databases like PubMed, Google Scholar, DOAJ and NIH with keywords such as herbal medicine, cancer, nanobiopolymers, and chitosan. Studies show chitosan is an effective carrier for active substances in cancer therapy, offering improved solubility, stability, and bioavailability. Nanobiopolymers, ranging from 0-1000 nm, serve as carriers for active compounds in cancer treatment. This literature review is expected to contribute to the understanding of the potential integration of herbal extracts with chitosan, particularly in the production of chitosan nanobiopolymers as carriers in cancer treatment.

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