Promising Medicinal Plants and their Potential Active Constituents for Healing of Superficial Burn Wounds- A Review

Nassar, Salah Lotfy; El Hawary, Seham Salah Eldin; Elgendy, Hussieny Abdelmohsen; El-Raey, Mohamed Abdelaziz; Kirollos, Farid Noshy

doi:10.21608/ejchem.2024.289838.9742

Promising Medicinal Plants and their Potential Active Constituents for Healing of Superficial Burn Wounds- A Review

Document Type : Review Articles

Authors

¹ Pharmacognosy Department, Faculty of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology

² Pharmacognosy Department, Faculty of Pharmacy, Cairo University

³ Department of Pharmacognosy, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology

⁴ Professor of Natural products Chemistry and Plant Systematics. Department of Phytochemistry and plant Systematic. National Research Centre.

⁵ department of pharmacognosy, faculty of pharmacy, Cairo university

10.21608/ejchem.2024.289838.9742

Abstract

Burn injuries represent a diverse and varied challenge to medical and paramedical staff. Correct management requires a skilled multidisciplinary approach that addresses all the problems facing a burn patient. The burn injury represents an assault on all aspects of the patient, from the physical to the psychological. It affects all ages, from babies to elder people, and is a problem in both the developed and developing world. This review aimed to summarize knowledge on the possible use of selected medicinal plants expected to treat superficial burns on basis of their promising active ingredients, achieving the treatment goals. Superficial and partial-thickness burns are the most common in pharmaceutical practice. The ideal natural treatment of such type of burn injuries that we would like to recommend should, in addition to healing properties, has the following properties: infection prevention, reducing wound inflammation, non-toxic, biocompatible and cost effective, so as to avoid progress of the superficial burn wounds into deeper ones and preventing serious local and general complications.

Medicinal plant extracts can compete with conventional burn treatments and potentially promote the treatment of burn wounds due to their diverse mechanism of action, antimicrobial activity, antiinflammatory effects, the safety of use and the cost effectiveness. The growing interest in alternative medicine encourages phytochemical and biological investigations of plant extractives expected to promote healing of superficial burn wounds, taking into accounts the use of not only single preparations but also their mixtures and Nano-formulations; as the research conducted so far often suggest a synergistic effect and Nano-formulations of the phytochemical ingredients such as volatile oils, sterols and flavonoids.

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