Novel Schiff base metal complexes and their biological applications Walaa H. Mahmoud 1 , Moustafa M. Goha1 , Taha M. Eldebss1 and Ahmed A. El-Sherif 1

Document Type : Original Article

Authors

1 Faculty of science, Cairo university

2 organic chemistry department, faculty of science , cairo university

3 chemistry, faculty of science, Cairo university

Abstract

Cr(III), Zn(II), Ni(II) and Cu(II) complexes of a symmetric Schiff base ligand (L), (Z)-N'-((1E,2E)-1-(2-(p-tolyl)hydrazineylidene)propan-2-ylidene)-2-((E)-1-(2-(p-tolyl)hydrazineylidene)propan-2-ylidene)hydrazine-1-carbohydrazide has been synthesized. Elemental analysis, UV-Visible, FT-IR, mass spectra and conductometric techniques were used to characterise the ligand and its metal complexes. The microorganisms utilized in this study involve Streptococcus mutans, Staphylococcus Aureus (as Gram-positive bacteria), Escherichia Col and Klebsiella pneumonia (as Gram-negative bacteria) and Aspergillus Nigar and Candida albicans (as fungi). Comparing all of the studied species, Cu(II) complex exhibits the highest activity versus tested fungi.

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Articles in Press, Accepted Manuscript
Available Online from 03 June 2024
  • Receive Date: 06 August 2023
  • Revise Date: 06 September 2023
  • Accept Date: 03 June 2024