Evaluation of the Halopitys incurvus algae essential oil as a wound-healing candidate: An animal study

Document Type : Original Article

Authors

1 Department of biology faculty of science Choaib Doukali el Jadida Morocco

2 Department of biology, Faculty of sciences Chouaib Doukkali, Eljadida, Morocco.

Abstract

The use of seaweed in medicine has been known since antiquity but remains limited. The skin is an organthat has essential roles for the good functioning of our body but also in the image we give to others. This study lies within the scope of the valorization of essential oil of Halopitys incurvus alga field as antioxidants and healing. The methods applied to measure the antioxidant activity were trapping of the free radicals by using the 1,1'-diphenyl-2-picrylhydrazyl (DPPH°); ferric reducing antioxidant power (FRAP): hydroxyl radical scavenging; production of substances reacting with thiobarbituric acid (TBARS) and the estimation of total phenolic content. For evaluation the healing activity we used induced surgical wounds in Wistar rats. The results obtained show that the essential oil of the red algae Halopitys incurvus has a very significant antioxidant activity with all the tests used, DPPH, FRAP, Hydroxyl radical, TBARS with the respective IC50 values 106.05 ± 0.41, 264.8 ± 0.28, 208.51 ± 0.85, 100 ± 91(μg/ml). Also we discovered a very important healing capacity on the wounds produced on the Wistar rats. The results obtained confirm a correlation between the phytochemical study, the antioxidant activity and the healing capacity that demonstrate the essential oil of the red algae Halopitys incurvus constitutes a reservoir of components with a very interesting effect in the healing process.

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History

  • Receive Date: 10 November 2022
  • Revise Date: 17 January 2023
  • Accept Date: 01 June 2024

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