Abstract: A new series of 2,4-disubstituted phthalazin-1(2H)-one derivatives was synthesized via nucleophilic attach of N-2 of phthalazin-1(2H)-one derivatives on different monosuccharides. Synthesis of phthalazinone nucleosides were very effective as antimicrobial. Also the phthalazinone moiety can be used in synthesis of reactive nucleosides and dyes that was chemically bonded with proteins and fibers respectively as afforded highly stability of dyestuff wool and cotton textiles. The structure of the prepared compounds was elucidated by physical and spectral data like FT-IR, 1H- and 13C-NMR.
EL-Hashash, M., Rizk, S., El-Bassiouny, F., Guirguis, D., Khairy, S., & Guirguis, L. (2017). Facile Synthesis and Structural Characterization of Some Phthalazin-1(2H)-one Derivatives as Antimicrobial Nucleosides and Reactive Dye. Egyptian Journal of Chemistry, 60(3), 407-420. doi: 10.21608/ejchem.2017.915.1043
MLA
Maher EL-Hashash; Sameh Rizk; Fakhri El-Bassiouny; Dalal Guirguis; Sherif Khairy; Laila Guirguis. "Facile Synthesis and Structural Characterization of Some Phthalazin-1(2H)-one Derivatives as Antimicrobial Nucleosides and Reactive Dye", Egyptian Journal of Chemistry, 60, 3, 2017, 407-420. doi: 10.21608/ejchem.2017.915.1043
HARVARD
EL-Hashash, M., Rizk, S., El-Bassiouny, F., Guirguis, D., Khairy, S., Guirguis, L. (2017). 'Facile Synthesis and Structural Characterization of Some Phthalazin-1(2H)-one Derivatives as Antimicrobial Nucleosides and Reactive Dye', Egyptian Journal of Chemistry, 60(3), pp. 407-420. doi: 10.21608/ejchem.2017.915.1043
VANCOUVER
EL-Hashash, M., Rizk, S., El-Bassiouny, F., Guirguis, D., Khairy, S., Guirguis, L. Facile Synthesis and Structural Characterization of Some Phthalazin-1(2H)-one Derivatives as Antimicrobial Nucleosides and Reactive Dye. Egyptian Journal of Chemistry, 2017; 60(3): 407-420. doi: 10.21608/ejchem.2017.915.1043
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