Evaluation of the Apiacupuncture Against the Damages and Erythrocyte Osmotic Fragility Induced by Oxidative Stress in Egyptian Patients with Chronic Neck Pain

Hegazi, Ahmed G.; Ibrahim, Fatma A. A.; Ganem, Mona M.F.; Abdel-Rahman, Eman H.; Aziz, Samir W.; Medhat, Amira; Monir, Rasha; El Gendy, Aliaa

doi:10.21608/ejchem.2023.210791.7976

Evaluation of the Apiacupuncture Against the Damages and Erythrocyte Osmotic Fragility Induced by Oxidative Stress in Egyptian Patients with Chronic Neck Pain

Document Type : Original Article

Authors

¹ Zoonotic Diseases Department, National Research Centre, Giza, 12622, Egypt.

² Department of Biochemistry, National Research Centre, Dokki, Cairo, 12622, Egypt

³ Internal Medicine, National Research Centre, Dokki, Cairo, 12622, Egypt

⁴ Parasitology Department, National Research Centre, Giza, 12622, Egypt.

⁵ Complementary Medicine Department, National Research Centre, Giza, 12622, Egypt.

10.21608/ejchem.2023.210791.7976

Abstract

Many people suffer from neck pain due to a sedentary lifestyle. It has become imperative to study dealing with neck pain in Oriental medicine. Thirty female patients diagnosed with chronic neck pain were subjected to this study & thirty healthy control. The mean of the Visual analog scale (VAS) and of the Neck Disability Index Questioner (NDIQ) were significantly decreased (P< 0.05) after bee venom therapy. Also a significant decrease in Oxidative stress markers after bee venom administration, where malondialdehyde (MDA) & Glutathione S-transferases (GST) activities were decreased after treatment. On the other hand, catalase activities after bee venom were increased with a significant difference (P<0.05). Moreover, bee venom acupuncture diminished the elevated average osmotic fragility and decreased the elevated rate of haemolysis. Results suggested that bee venom could be a supportive antioxidant that plays an important role in damage control caused by oxidative stress. It can be concluded that Bee venom pharm-acupuncture has been reported to be effective in treating and dominating neck pain.

The aim of this study was to evaluate the role of bee venom acupuncture in chronic neck pain patients, concerning pain intensity and supported lifestyle quality with controlling oxidative damage.

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