The previously described 6,8-dibromo-2-(3,4-dichlorophenyl)quinazolin-4(3H)-one 1 was created and employed as a building block for the synthesis of quinazolinone derivatives 2–11 with considerable predicted medicinal activity. The reaction of the hydrazinyl derivative 9 with carbon disulfide led to the 7,9-dibromo-5-(3,4-dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazoline-3(2H)-thione 12. From the compound 6,8-dibromo-2-(3,4-dichlorophenyl)quinazoline-4(3H)-thione 8 came the quinazolinone derivatives 13–16. Physical and chemical methods were used to characterize constructed products.
Elbadry, M., & El-Ziaty, A. (2023). Design Synthesis and Characterization of Novel Quinazolin-4(3H)-one Derivatives with Anticipated Pharmacological Efficacy. Egyptian Journal of Chemistry, 66(6), 493-498. doi: 10.21608/ejchem.2023.207385.7905
MLA
Mohamed Elbadry; Ahmed Kamel El-Ziaty. "Design Synthesis and Characterization of Novel Quinazolin-4(3H)-one Derivatives with Anticipated Pharmacological Efficacy". Egyptian Journal of Chemistry, 66, 6, 2023, 493-498. doi: 10.21608/ejchem.2023.207385.7905
HARVARD
Elbadry, M., El-Ziaty, A. (2023). 'Design Synthesis and Characterization of Novel Quinazolin-4(3H)-one Derivatives with Anticipated Pharmacological Efficacy', Egyptian Journal of Chemistry, 66(6), pp. 493-498. doi: 10.21608/ejchem.2023.207385.7905
VANCOUVER
Elbadry, M., El-Ziaty, A. Design Synthesis and Characterization of Novel Quinazolin-4(3H)-one Derivatives with Anticipated Pharmacological Efficacy. Egyptian Journal of Chemistry, 2023; 66(6): 493-498. doi: 10.21608/ejchem.2023.207385.7905
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