Kappa carrageenan (КC) is sulfated polysaccharides and can be crosslinked by K+ ions to obtain biohydrogel having a biodegradable nature as well as excellent cytocompatibility. Crosslinking of KC with K+ ions converts it to strong and brittle gel. In that study, non-woven cotton fabric samples (NWCF) were quaternized to achieve QNWCF samples which were then re-treated with different polyethylene glycol/Kappa carrageenan (PEG/КC) blending ratios and crosslinked with K+ ions to achieve КC/PEG/K+/QNWCF wound dressings. The results depict that the appropriate conditions to achieve that dressing is: PEG/KC weight ratio, 0.25%; K+ padding bath concentration, 1%; and immersion time, 10 min. The chemical structure of such dressing was confirmed via FTIR while its morphology was analyzed using scan electron microscope. The sulfadiazine in-vitro releasing from the loaded dressing at pH 7 was investigated. The results confirm that the prepared sulfadiazine loaded dressing has significant antibacterial activities that were remarkably enhanced upon addition of silver nano-particle during the dressing preparation.
Aly, A., Fahmy, H., & Abou-Okeil, A. (2023). κ-carrageenan/poly(ethylene glycol) Based Non-woven Cotton Wound Dressings. Egyptian Journal of Chemistry, 66(9), 159-168. doi: 10.21608/ejchem.2023.174924.7198
MLA
A. A. Aly; H.M. Fahmy; A. Abou-Okeil. "κ-carrageenan/poly(ethylene glycol) Based Non-woven Cotton Wound Dressings". Egyptian Journal of Chemistry, 66, 9, 2023, 159-168. doi: 10.21608/ejchem.2023.174924.7198
HARVARD
Aly, A., Fahmy, H., Abou-Okeil, A. (2023). 'κ-carrageenan/poly(ethylene glycol) Based Non-woven Cotton Wound Dressings', Egyptian Journal of Chemistry, 66(9), pp. 159-168. doi: 10.21608/ejchem.2023.174924.7198
VANCOUVER
Aly, A., Fahmy, H., Abou-Okeil, A. κ-carrageenan/poly(ethylene glycol) Based Non-woven Cotton Wound Dressings. Egyptian Journal of Chemistry, 2023; 66(9): 159-168. doi: 10.21608/ejchem.2023.174924.7198
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