Cellulose powder / poly (N-vinyl-2-pyrrolidone) (CP/PVP) and carboxymethylcellulose / poly (N-vinyl-2-pyrrolidone) (CMC/PVP) hydrogels were synthesized at different reaction conditions using ammonium persulphate as initiator. The optimum reaction conditions to prepare such gels are PVP molecular weight (40000 Dalton), PVP concentration (60%), APS/polymers weight ratio (100%), reaction time (45 min), reaction temperature (90 OC), as well as CP/PVP or CMC/PVP weight ratio (25%). The prepared matrices were characterized via FTIR as well as scan electron microscope analysis. The release profiles of sodium diclofenac form the CP/PVP and CMC/PVP gels at pH 7 were studied. Release studies showed burst release for both matrices at first 30 min followed by sustained behavior. matrices PVP/CMC showed highest release of DS due to repulsive forces between polymer chains.
Fahmy, H., & Montaser, A. (2023). Preparation and characterization of cellulose/poly (N-vinyl-2-pyrrolidone) hydrogels. Egyptian Journal of Chemistry, 66(9), 245-255. doi: 10.21608/ejchem.2022.174496.7216
MLA
H.M. Fahmy; A.S. Montaser. "Preparation and characterization of cellulose/poly (N-vinyl-2-pyrrolidone) hydrogels". Egyptian Journal of Chemistry, 66, 9, 2023, 245-255. doi: 10.21608/ejchem.2022.174496.7216
HARVARD
Fahmy, H., Montaser, A. (2023). 'Preparation and characterization of cellulose/poly (N-vinyl-2-pyrrolidone) hydrogels', Egyptian Journal of Chemistry, 66(9), pp. 245-255. doi: 10.21608/ejchem.2022.174496.7216
VANCOUVER
Fahmy, H., Montaser, A. Preparation and characterization of cellulose/poly (N-vinyl-2-pyrrolidone) hydrogels. Egyptian Journal of Chemistry, 2023; 66(9): 245-255. doi: 10.21608/ejchem.2022.174496.7216
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