Current Development in Peptide Surrogates Synthesis and Their Biological Applications

Document Type : Review Articles

Authors

1 Peptide Chemistry Department, Chemical Industries Research Division, National Research Centre, 12622- Dokki, Cairo, Egypt

2 Peptide Chemistry Department, Chemical Industries Research Division, National Research Centre, 12622-Dokki, Cairo, Egypt.

Abstract

Many new peptide therapeutics are increasingly making their way to rapid and successful clinical application. In fact, some naturally derived peptide chains were used as effective drugs for several years. With the emergence of very large libraries of peptides with high biological properties, it is expected that several potential candidates will be introduced to the list of under-development peptides, introducing new drug-administration strategies derived from polypeptide chains and improvements in the purification half-life in vivo. Despite remaining potential hurdles, peptide therapies are poised to play an important role in treating diseases ranging from Alzheimer's disease to cancer.

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History

  • Receive Date: 01 September 2022
  • Revise Date: 10 October 2022
  • Accept Date: 14 November 2022

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