Synthesis, characterization and biological activity of Co(II), Ni(II), Cu(II) and Cd(II) complexes with new imidazole derivatives [ethyl {[5-oxo-1-(phenylcarbonyl)-4-(prop-1-en-2-yl)-4,5-dihydro-1H-imidazol-2-yl]sulfanyl}acetate]

Abdullah, Sallal; Faeq, Rana; Kadhem, Noor; Mohsen, Saif; Kadham, Sahar

doi:10.21608/ejchem.2022.152031.6586

Synthesis, characterization and biological activity of Co(II), Ni(II), Cu(II) and Cd(II) complexes with new imidazole derivatives [ethyl {[5-oxo-1-(phenylcarbonyl)-4-(prop-1-en-2-yl)-4,5-dihydro-1H-imidazol-2-yl]sulfanyl}acetate]

Document Type : Original Article

Authors

¹ Chemistry division, Applied Science department, University of Technology, Iraq

² Department of Chemistry, College of Sciences/Al- Mustansiriyha University, Iraq.

³ forensic legal department, Iraq

10.21608/ejchem.2022.152031.6586

Abstract

The new imidazole ligand have been synthesized from reaction of benzoyl chloride with thiourea, then the resulting product reacted with ethylchloroacetate to produced [ethyl {[4-oxo-1-(phenylcarbonyl)-5-(prop-1-en-2-yl)-4,5-dihydro-1H-imidazol-2-yl]sulfanyl}acetate], This ligand was characterized by C.H.N.S (Elemental analysis), 1H-NMR spectrum, FT-IR spectrum and UV-visible spectra . Metal complexes of this ligand were synthesized and characterized by C.H.N.S (elemental analysis), Magnetic susceptibility, electrical conductance, UV-Vis spectra and FT-IR spectra. The synthesized compounds were screened for its antibacterial and antifungal activity. The result showed that these complexes inhibited the growth of the tested organism

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