Chemical and biological studies of Thyme based on different solvents extraction

Document Type : Original Article

Authors

Faculty of Specific Education, Zagazig University, Zagazig, 44519, Egypt.

Abstract

Thyme was employed in this work to analyze the overall composition using its methanolic and ethanolic extracts. protocatechuic acid, p-hydroxybenzoic acid, rosmarinic acid, cateachin, caffeic acid, apigenin, kaempferol, ferulic acid, and rutin were the most potant bioactive compounds of thyme extracts. These substances have antimicrobial properties against G+ bacteria and G- bacteria. It is also necessary to test thyme and its extracts for their efficacy in vivo in order to confirm the findings of the current investigation. With respect to G+ bacteria (Bacillus cereus and Staphylococcus aureus), G- bacteria (Escherichia coli and Pseudomonas aeruginosa), and fungi (Candida albicans), the ethanolic and methanolic extracts have anti-microbial activity (Ampicillin as antibacterial agent and Amphotericin B as antifungal agent).

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