Synthesis and Antimicrobial Activity of Copper and Zinc Complexes based on Benzimidazole scaffold

Document Type : Original Article

Authors

1 Organometallic and Organometalloid Chemistry Department, National Research Centre, Cairo, Egypt.

2 national Research Centre, ElBohouth St., Dokki, Giza, Egypt P.O. 12622

3 National research Center

4 National Research Centre

Abstract

The fundamental goal of the present study was carried out to generate novel metal complexes based on benzimidazole (BI) as a precursor with Cu and Zn cations. Herein, Cu-BI and Zn-BI complexes were prepared and characterized via Fourier transform infrared spectroscopy (FT-IR), UV–visible, 1H NMR, and mass spectra. Moreover, antimicrobial activity of the benzimidazole, the zinc, and copper complexes was evaluated using different methods as disc agar and colony forming techniques. The obtained results revealed that the Cu-BI complex could offer the best antimicrobial activity.

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History

  • Receive Date: 24 July 2022
  • Revise Date: 14 August 2022
  • Accept Date: 15 August 2022

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