Study of Thermal Behavior and Anti-Breast Cancer Activity of Some New Lignin-Nanoparticle Networks Sustained with Triterpenoid Compound Isolated from Calotropis procera L. leaves

Document Type : Original Article

Authors

1 Department of Chemistry, College of Science, University of Basrah, Basrah, Iraq

2 Chemistry, Collage of science, University of Basrah, Iraq

Abstract

Abstract
The aim of the present study is to provide breast cancer antibiotic from compound extracted from a cheap and available local plant (Calotropis procera L.) and preparation new two interpenetrating polymer networks(IPNs) based on biopolymer product, nature (lignin nanoparticles LNPs) and manufactured as methacrylic acid (MAA) and 2-(Dimethylamino)ethyl methacrylate (DMAEMA) were identified and evaluated by IR, thermal analysis (TGA) and scanning electron microscopy(SEM) to carry the plant extract. The efficacy of all plant extract, LNPs, and IPNs for the extract was tested using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT assay) on the MCF-7 cell line for 72 h and different concentrations. We found that all models gave different lethal effect to the cells

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History

  • Receive Date: 13 December 2018
  • Revise Date: 27 December 2018
  • Accept Date: 16 January 2019

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