In this work new heterocyclic derivatives were prepared. The most available (Sulfadiazine) compound treated with different aromatic aldehydes to synthesis (F1-F5) imine derivatives then cycloaddition reaction of imines with phenylthioacetic acid to produced azetidin-2-one derivatives(F6,F7). compound F1 treated ethylene glycol and hydrazine to get (F8) . (F9,F10) compounds has been synthesis by reacting (F1) compound with maleic anhydride and phthalic anhydride in dry benzene . compound F8 treated p-hydroxy benzaldehyde to get (F11) compound. Reaction (F11) with benzoyl chloride gave (F12) compound. Also, (F12) compound treated with urea to get urease derivative .These synthesized compounds (F1-F13) evaluated for their antimicrobial activity and antioxidant activity.
Lihumis, H. S., Alameri, A., & Zaooli, R. (2023). Design, Synthesis of Sulfadiazine Derivatives bearing Some New Heterocyclic Compounds with study Antimicrobial and Antioxidant Activity. Egyptian Journal of Chemistry, 66(2), 81-91. doi: 10.21608/ejchem.2022.131305.5787
MLA
Hala Shkyair Lihumis; Ameer Alameri; Rawaa Zaooli. "Design, Synthesis of Sulfadiazine Derivatives bearing Some New Heterocyclic Compounds with study Antimicrobial and Antioxidant Activity". Egyptian Journal of Chemistry, 66, 2, 2023, 81-91. doi: 10.21608/ejchem.2022.131305.5787
HARVARD
Lihumis, H. S., Alameri, A., Zaooli, R. (2023). 'Design, Synthesis of Sulfadiazine Derivatives bearing Some New Heterocyclic Compounds with study Antimicrobial and Antioxidant Activity', Egyptian Journal of Chemistry, 66(2), pp. 81-91. doi: 10.21608/ejchem.2022.131305.5787
VANCOUVER
Lihumis, H. S., Alameri, A., Zaooli, R. Design, Synthesis of Sulfadiazine Derivatives bearing Some New Heterocyclic Compounds with study Antimicrobial and Antioxidant Activity. Egyptian Journal of Chemistry, 2023; 66(2): 81-91. doi: 10.21608/ejchem.2022.131305.5787
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