Therapeutic Effect of Equisetum arvense L. on Bone and Scale Biomarkers in Female Rats with Induced Osteoporosis

Document Type : Original Article


1 Regional Center for Food and Feed, Agricultural Research Center, Giza, Egypt

2 Nutrition and Food Science Dept, Faculty of Home Economics, Helwan University, Cairo, Egypt.


Equisetum arvense L. (common horsetail) has medicinal characteristics that have been known since ancient times and are used to cure a variety of ailments. The effect of E. arvense L. on rats with induced osteoporosis was investigated. Forty female rats were randomized in 5 equal groups (n=8). The first group was working as tricks (SHAM) (negative control), while the other 4 groups were operating with ovariectomized (OVX) and fed on basal diet deficient in calcium and were given orally prednisone acetate (4.5 ml/kg body weight/day twice a week) for two weeks as source of glucocorticoid, to induce osteoporotic models. Three weeks after ovarian removal, Group 2 kept as positive control (OVX) and the other three groups were fed on basal diet supplemented with 5, 10 and 15% of dried E. arvense L, respectively for 8 weeks. The results showed that rats fed on dried E. arvense at all tested levels had significant increase (P


Main Subjects