Nano micelle: Novel Approach for Targeted Ocular Drug Delivery System

Document Type : Original Article

Authors

1 Shri Ram Murti Smarak College of Engineering and Technology (Pharmacy), Bareilly-243202, (U.P.), India.

2 Dr. B C Roy College of Pharmacy & AHS, Dr. Meghnad Saha Sarani, Bidhannagar, Durgapur, West Bengal- 713206, India.

3 Department of Pharmaceutical Technology, Brainware University, 398-Ramkrishnapur Road, Barasat, Kolkata-700125, West Bengal, India

4 Department of Pharmacy, Sanaka Educational Trust`s Group of Institutions, West Bengal713212, India

Abstract

Ocular delivery like all other systems is challenging for the researchers as one can instill drug into the eye but can never ensure the correct amount reaches the eye. Ophthalmology for all these reasons has commenced its dependence on novel techniques. Ocular through novel becomes a boon as you can deliver huge amounts or you can deliver as per the need but it’s always a tricky one as you need more residence of the drug in the eye for better action, but the lacrimal drainage and rejuvenation spoils all novel thoughts and leads the novel with surface modification. The surface of the particles needs to be adhering to the surface of the eye or in the cul de sac as with more drug amount we need more residence for action.
This research work provides a better way for ocular drug delivery to the eye through a novel system, i.e., Nano micelle which consists of tri-block copolymerization with fluoroquinolones for treating gall bacterial infections of the eye. The work is based on how we have employed the nano micelle of a fluoroquinolone for ocular delivery that adheres in the eye and delivers the drug for a period more which cannot be expected through the conventional system.

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History

  • Receive Date: 30 January 2022
  • Revise Date: 17 February 2022
  • Accept Date: 14 March 2022

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