An Improved Sensitive and Selective Non-enzymatic Glucose Biosensor Based on PEG Assisted CuO Nanocomposites

Mohamed Azharudeen, AbdulSalam; Suriyakala, Thevaraj; Rajarajan, Muthuramalingam; Suganthi, Ayyadurai

doi:10.21608/ejchem.2018.5707.1489

An Improved Sensitive and Selective Non-enzymatic Glucose Biosensor Based on PEG Assisted CuO Nanocomposites

Document Type : Original Article

Authors

¹ Department of Chemistry C.P.A. College, Bodinayakanur, Theni District, TamilNadu.

² Department of Chemistry, Madurai Kamaraj University, Madurai-625021. TamilNadu, India.

³ Mother Teresa Women&#039;s University, Kodaikanal, Dindugal District. TamilNadu.

10.21608/ejchem.2018.5707.1489

Abstract

Determination of glucose is of enormous importance in the fields of biological, environmental and clinical analyses. In recent years, polymer modified metal oxides arrived a great consideration in the detection of glucose. In this study, we have developed a sensitive and selective non-enzymatic glucose sensor by using CuO NMO encapsulation with PEG (poly ethyleneglycol) nanocomposites. The loading content of PEG was incorporated with CuO by weight percentage (wt = 2, 4 & 6%). The fabricated CuO/PEG nanocomposites was utilized as a glucose sensor, it exhibit the tremendous electrocatalytic performances on oxidation of glucose. The electrocatalytic activity enhances with increasing the loading of PEG content. The sensor shows a low detection limit of 0.25 µM with a sensitivity of 113.8 µA mM-1 cm-2, good selectivity and stability. The CuO/PEG nanocomposites are hopeful for the advancement of cost-effective non-enzymatic glucose biosensors.

Keywords