Validation using QuEChERS method, risk assessment and preharvest intermission using GC-MS for determination of azoxystrobin in tomato and cucumber

Elhefny, Dalia Elsayed; Hunter, Hany; Helmy, Rania Mohamed Ahmed

doi:10.21608/ejchem.2021.76725.3756

Validation using QuEChERS method, risk assessment and preharvest intermission using GC-MS for determination of azoxystrobin in tomato and cucumber

Document Type : Original Article

Authors

¹ Pesticides Residues and Environmental Pollution, Central Agricultural Pesticides Laboratory, Agricultural Research Center, Giza, Egypt

² Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini street 11562, Egypt

³ Pesticide Residues and Environmental Pollution department, Central Agricultural Pesticide Laboratory, Agricultural Research Center,12618 Giza, EGYPT

10.21608/ejchem.2021.76725.3756

Abstract

Azoxystrobin residues in tomatoes and cucumbers was accurately determined by gas chromatography / mass spectrometry (GC-MS) in the selective ion monitoring (SIM) mode (the selected ion: m/z 344, 372, 388 and 403). The average recoveries at three levels came to range from 83.92% to 95.77% with a relative standard deviation of less than 20.0%. The limit of detection and the limit of quantitation were 0.01 and 0.05 mg kg-1. Furthermore, the residues in tomatoes and cucumbers were estimated over 15 days. As for half lives, they were shown to be rated between 1.69 and 4.5 days for both tomatoes and cucumbers after the application with recommended and double recommended dose, and found to be less than maximum residue limit so it can be recommended as preharvest gap. The dietary intake was not found to be abiding by the maximum permissible intake for both recommended or even double recommended dose, as it was found that both were less than the maximum permissible intake; which leads a vast improvement in azoxystrobin human health safety satisfaction.

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