Correlation Of Ghrelin And C-Peptide Hormones And Some Other Biochemical Factors With Women Obesity

Document Type : Original Article

Authors

University of Mosul, College of Science, Department of Chemistry, Mosul, Iraq.

Abstract

The study was conducted of National Center for Obesity Treatment in Mosul city, from December 2020 to March 2021. The study included (112) woman whose age range between (15-55→) year, (84) of them were obese women and (28) of them were women with normal weight, depending on body mass index BMI value. They were divided into four age groups [(15-25), (25-35), (35-45), (45-55→) year]. All women (not suffering from diabetic mellitus or heart diseases). Blood samples were collected from women whose fasting period of (12-14) hour, serum samples were separated and stored in capped tubes, then we measured the level of Ghrelin hormone, lipid profile [total cholesterol (TC), Triglyceride (TG), High density lipoprotein (HDL), Low density lipoprotein (LDL), Very low-density lipoprotein (VLDL), Atherogenic index (AI)], and measured the level of C-peptide hormone and Glucose (to calculate insulin resistance). The results indicated that the level of ghrelin hormone decreased in obesity (the differences between control and obese groups were significant at P≤0.05) but lipid profile and insulin resistance increased except HDL decrease in obesity (the differences between control and obese groups were significant at P≤0.05).
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