The research resulted in the production of new tetrazoline derivatives. Firstly; the reaction of N-acetyl chloro cyclic imides with hydrazine hydrate to give compounds (1,2). Then, compounds (1,2) were reacted with different aromatic aldehydes to give Schiff bases (3-10). The compounds of N-( 2-chloro acetyl) cyclic imides were reacted with sodium azide to give N-(azido acetyl) cyclic imides (11,12). Finally, the reaction of the prepared Schiff bases compounds with azide compounds and cyclization to gave 5-aryl tetrazoline on cyclic imides (13-20). The prepared compounds were characterized by Fourier transform infrared spectroscopy (FT-IR) and some of them byProton nuclear magnetic resonance (1H-NMR), melting point, and were studied the effects of the preparing compounds on some strains of bacteria and fungi.
Al-Haidari, A., & AL-Tamimi, E. (2021). Synthesis of New 5-Aryl Tetrazoline from N-Aceto Hydrazide Cyclic Imides and Study of Biological Activity. Egyptian Journal of Chemistry, 64(10), 5647-5653. doi: 10.21608/ejchem.2021.70531.3554
MLA
Akram Al-Haidari; Entesar AL-Tamimi. "Synthesis of New 5-Aryl Tetrazoline from N-Aceto Hydrazide Cyclic Imides and Study of Biological Activity". Egyptian Journal of Chemistry, 64, 10, 2021, 5647-5653. doi: 10.21608/ejchem.2021.70531.3554
HARVARD
Al-Haidari, A., AL-Tamimi, E. (2021). 'Synthesis of New 5-Aryl Tetrazoline from N-Aceto Hydrazide Cyclic Imides and Study of Biological Activity', Egyptian Journal of Chemistry, 64(10), pp. 5647-5653. doi: 10.21608/ejchem.2021.70531.3554
VANCOUVER
Al-Haidari, A., AL-Tamimi, E. Synthesis of New 5-Aryl Tetrazoline from N-Aceto Hydrazide Cyclic Imides and Study of Biological Activity. Egyptian Journal of Chemistry, 2021; 64(10): 5647-5653. doi: 10.21608/ejchem.2021.70531.3554
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