Abstract The idea of this work is to determine of Ceftriaxone sodium (CFT) through the development and verification of a accurate and rapid isocratic of RP-HPLC method using a C18 as stationary phase column. The mobile phase was described as a mixture of 80:20 Buffer:methanol. The optimum conditions for estimation were; column temperature 30 °C and mobile phase flow rate of 0.7 mL/min. by using the UV-detection at a 241nm wavelength. The analysis data showed that the determination coefficient, R2 was 0.9985, detectioin limit of 4.3 x 10−6 µg/mL and limit of quantification of 1.4 x 10−5 µg/mL. This developed method was successfully examined for the estimate of ceftriaxone sodium in their pure form and in numeral commercial pharmaceuticals preparations with little interference of additives.
Salman, A. (2021). RP- HPLC Estimation of Ceftriaxone Sodium in Pharmaceuticals. Egyptian Journal of Chemistry, 64(9), 4901-4906. doi: 10.21608/ejchem.2021.68537.3504
MLA
Abbas Talib Salman. "RP- HPLC Estimation of Ceftriaxone Sodium in Pharmaceuticals", Egyptian Journal of Chemistry, 64, 9, 2021, 4901-4906. doi: 10.21608/ejchem.2021.68537.3504
HARVARD
Salman, A. (2021). 'RP- HPLC Estimation of Ceftriaxone Sodium in Pharmaceuticals', Egyptian Journal of Chemistry, 64(9), pp. 4901-4906. doi: 10.21608/ejchem.2021.68537.3504
VANCOUVER
Salman, A. RP- HPLC Estimation of Ceftriaxone Sodium in Pharmaceuticals. Egyptian Journal of Chemistry, 2021; 64(9): 4901-4906. doi: 10.21608/ejchem.2021.68537.3504
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