Synthesis of Dibenzofuran Derivatives Possessing Anti-bacterial Activities

Document Type : Review Articles

Author

Peptide Chemistry Department, Chemical Industries Research Division, National Research Centre, 12622-Dokki, Cairo, Egypt.

Abstract

Dibenzofuran (DBF) are typical heterocyclic aromatic compounds (O-HETs), which can coexist with polycyclic aromatic hydrocarbons (PAHs) in combustion and pyrolysis conditions. In this review, Emphasis has already been placed on the reports on synthesis of dibenzofuran derivatives with possessing anti-bacterial activities. It is not a comprehensive discussion of all such compounds, but is instead intended to illustrate the range of anti-bacterial activity possessed by such compounds, the variety of sources from which they can be synthesized, and the various synthetic methods by which they can be prepared. Compounds with reduced benzene rings (such as morphine and its derivatives) are not included in this review, nor are compounds in which an aromaticity is disrupted by alkylation, as with usnic acid.

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