Effectiveness of Magnesium oxide Nanoparticles in the Management of Thyroid Hormone Level

Document Type : Original Article

Authors

1 Department of Chemistry, College of Science, Al-Nahrain University, Baghdad, Iraq

2 Department of Chemistry, College of Science, Al- Mustansiriyah University, Baghdad, Iraq

Abstract

Hypothyroidism is a clinical dysfunction resulting from deficiency of thyroid hormones or, more rarely, from their impaired and it poses a threat to human health. Nanotechnology is being applied for the inorganic biomedical agents development due to the perfect biological activities of the nanoparticles.Nanoinorganic metal oxides control the biological contaminants. The most widely utilized oxide in different fields is magnesium oxide nanoparticles. This work presents an investigation of the main synthesis method, characterization by several techniques, including Fourier transform infrared spectroscopy, Atomic Force Microscope, scanning electron microscopy and X-Ray Diffraction and the effect of magnesium oxide nanoparticles on serum levels of T4 hormone was investigated. Serum levels of T4 in experimental showed a significant decrease at 100 ppm compared to control group. Other concentrations did not change significantly compared to control group. Magnesium oxide nanoparticles (MgONPs) at concentration of 100 ppm reduced the serum T4 level.

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History

  • Receive Date: 26 December 2020
  • Revise Date: 13 February 2021
  • Accept Date: 14 March 2021

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