Synthesis and Antitumor Activity Evaluation of New 2-(4-aminophenyl) benzothiazole/oxazole/imidazole Derivatives

Abstract

A NEW series of 2-(4-aminophenyl)benzothiazole and related structure compounds, bearing thiocyanate, thiol in the 3'postion as well as new condensed benzothiazoles and related structure compounds having thiazolones ,tetrazole, oxadiazole have been synthesized . All the newly synthesized compounds were screened for their anti-tumor activities. The results revealed promising effects against most of the cancer cell lines.

Keywords


Volume 59, Issue 6 - Serial Number 6
December 2016
Pages 967-984
  • Receive Date: 16 October 2016
  • Revise Date: 28 November 2016
  • Accept Date: 29 November 2016
  • First Publish Date: 31 December 2016