Ali, K., Shihab, N., saeed, B. (2021). Synthesis, Identification and Study of the Anti-microbial Activity of Novel Chalcone and Epoxy Chalcone Compounds. Egyptian Journal of Chemistry, 64(5), 2297-2304. doi: 10.21608/ejchem.2021.57012.3233
Kawkab Ali; Nezar latif Shihab; Bahjat ali saeed. "Synthesis, Identification and Study of the Anti-microbial Activity of Novel Chalcone and Epoxy Chalcone Compounds". Egyptian Journal of Chemistry, 64, 5, 2021, 2297-2304. doi: 10.21608/ejchem.2021.57012.3233
Ali, K., Shihab, N., saeed, B. (2021). 'Synthesis, Identification and Study of the Anti-microbial Activity of Novel Chalcone and Epoxy Chalcone Compounds', Egyptian Journal of Chemistry, 64(5), pp. 2297-2304. doi: 10.21608/ejchem.2021.57012.3233
Ali, K., Shihab, N., saeed, B. Synthesis, Identification and Study of the Anti-microbial Activity of Novel Chalcone and Epoxy Chalcone Compounds. Egyptian Journal of Chemistry, 2021; 64(5): 2297-2304. doi: 10.21608/ejchem.2021.57012.3233
Synthesis, Identification and Study of the Anti-microbial Activity of Novel Chalcone and Epoxy Chalcone Compounds
1Department of Chemistry, College of Education for Pure Sciences, University of Basrah , Basrah, Iraq
2Department of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.
Receive Date: 14 January 2021,
Revise Date: 06 February 2021,
Accept Date: 11 February 2021
Abstract
Abstract In this study, new chalcone and epoxy chalcone synthesized by condensation of 4-acetylbiphenyl with the appropriate aldehydes. The epoxy chalcone prepared via the reaction chalcone with alkaline hydrogen peroxide in methanol. We characterized their mass spectra and 1H, 13C-NMR, and 2D-HSQC spectra to confirm their structure and absolute configuration. The target compounds were then screened for their potential antibacterial and antifungal activities. Most of the tested chalcone compounds had better activity against the fungal strains Fusarium and Aspergillus niger.
Top