Synthesis, Identification and Study of the Anti-microbial Activity of Novel Chalcone and Epoxy Chalcone Compounds

Document Type : Original Article

Authors

1 Department of Chemistry, College of Education for Pure Sciences, University of Basrah , Basrah, Iraq

2 Department of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.

Abstract

Abstract
In this study, new chalcone and epoxy chalcone synthesized by condensation of 4-acetylbiphenyl with the appropriate aldehydes. The epoxy chalcone prepared via the reaction chalcone with alkaline hydrogen peroxide in methanol. We characterized their mass spectra and 1H, 13C-NMR, and 2D-HSQC spectra to confirm their structure and absolute configuration. The target compounds were then screened for their potential antibacterial and antifungal activities. Most of the tested chalcone compounds had better activity against the fungal strains Fusarium and Aspergillus niger.

Keywords

Egyptian Journal of Chemistry
Volume 64, Issue 5
May 2021
Pages 2297-2304

Files

Cited by

History

  • Receive Date: 14 January 2021
  • Revise Date: 06 February 2021
  • Accept Date: 11 February 2021

Share

How to cite

Statistics