6-AMINOURACIL-2-THIONE (1) and its 5-bromo derivative 2 underwent alkylation yielding their respective S-alkyl products 4a-j. The reaction of compound 1 and aldehydes in the presence of chloroacetic acid afforded the respective thiazolopyrimidinyl acetamides 7a-d. The C-glycosides 8a,b and 9c-e were successfully prepared through condensing compound 1 and the appropriate sugar in the presence of chloroacetic acid. The behavior of certain S-alkyl derivative 4 towards amines and hydrazines was also studied. Structure elucidations for the new products were supported by compatible chemical and spectral measurements.
(2016). Chemical Synthesis of Some Novel 6-Aminouracil-2-Thiones and Their Glycoside Analogues. Egyptian Journal of Chemistry, 59(5), 779-797. doi: 10.21608/ejchem.2016.1449
MLA
. "Chemical Synthesis of Some Novel 6-Aminouracil-2-Thiones and Their Glycoside Analogues", Egyptian Journal of Chemistry, 59, 5, 2016, 779-797. doi: 10.21608/ejchem.2016.1449
HARVARD
(2016). 'Chemical Synthesis of Some Novel 6-Aminouracil-2-Thiones and Their Glycoside Analogues', Egyptian Journal of Chemistry, 59(5), pp. 779-797. doi: 10.21608/ejchem.2016.1449
VANCOUVER
Chemical Synthesis of Some Novel 6-Aminouracil-2-Thiones and Their Glycoside Analogues. Egyptian Journal of Chemistry, 2016; 59(5): 779-797. doi: 10.21608/ejchem.2016.1449
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