Synthesis, Characterization and Biological Activity of Some Pyrazole-Pyrazolone Derivatives


SIX heterocyclic compounds were synthesized based on pyrazole …. and pyrazolone rings. The chemical structures of the synthesized compounds were characterized by using: elemental analysis, FTIR, 1H-NMR, 13C-NMR and Mass spectra. The compounds were evaluated for their activity against gram +ve, gram –ve bacteria and fungi. The antimicrobial assessment showed the high activity of compounds I and VI.