3-(3,4-DICHLORO (or 3,4-dimethyl)benzoyl)] prop-2-enoic acids 1 ..... react with o-xylene and p-xylene under Friedel-Craft's reaction conditions giving acids 2 or 3, respectively. They were converted into the corresponding pyridazinone 4 derivatives upon treatment with N2H4 in boiling ethanol . The pyridazine derivatives 9,10,11 can be synthesized as a pro-drug due to their more potent and less peripheral effects than non-acidic or weakly acidic NSAIDs. Also, triazolopyridazine, oxazinone and furanone were also investigated.
(2012). 2- (3, 4- Dimethylphenyl - 3- [3, 4-Dichloro (or 3, 4-Dimethyl) Benzoyl])-Propanoic Acids as Precursors in the Synthesis of Some Heterocyclic Compounds. Egyptian Journal of Chemistry, 54(5), 579-593. doi: 10.21608/ejchem.2012.1427
MLA
. "2- (3, 4- Dimethylphenyl - 3- [3, 4-Dichloro (or 3, 4-Dimethyl) Benzoyl])-Propanoic Acids as Precursors in the Synthesis of Some Heterocyclic Compounds", Egyptian Journal of Chemistry, 54, 5, 2012, 579-593. doi: 10.21608/ejchem.2012.1427
HARVARD
(2012). '2- (3, 4- Dimethylphenyl - 3- [3, 4-Dichloro (or 3, 4-Dimethyl) Benzoyl])-Propanoic Acids as Precursors in the Synthesis of Some Heterocyclic Compounds', Egyptian Journal of Chemistry, 54(5), pp. 579-593. doi: 10.21608/ejchem.2012.1427
VANCOUVER
2- (3, 4- Dimethylphenyl - 3- [3, 4-Dichloro (or 3, 4-Dimethyl) Benzoyl])-Propanoic Acids as Precursors in the Synthesis of Some Heterocyclic Compounds. Egyptian Journal of Chemistry, 2012; 54(5): 579-593. doi: 10.21608/ejchem.2012.1427
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