SAERIES of new 1,4-benzoxazepin-5(4H)-ones was prepared by …….alkylation of salicylamides with phenacyl bromides followed by cyclodehydration of the resulting amides. Treatment of the 1,4-benzoxazepine-5(4H)-ones with phosphorus pentasulphide afforded the corresponding 1,4-benzoxazepine-5(4H)-thiones. N-alkylation of the 1,4- benzoxazepin-5(4H)-ones and S-alkylation of the 1,4-benzoxazepine-5(4H)-thiones were described. Some of the new compounds were subjected to preliminary screening for their tranquilizing effect.
(2011). Synthesis and Tranquillizing Effect of New 1,4-Benzoxazepines. Egyptian Journal of Chemistry, 54(4), 565-578. doi: 10.21608/ejchem.2011.1411
MLA
. "Synthesis and Tranquillizing Effect of New 1,4-Benzoxazepines". Egyptian Journal of Chemistry, 54, 4, 2011, 565-578. doi: 10.21608/ejchem.2011.1411
HARVARD
(2011). 'Synthesis and Tranquillizing Effect of New 1,4-Benzoxazepines', Egyptian Journal of Chemistry, 54(4), pp. 565-578. doi: 10.21608/ejchem.2011.1411
VANCOUVER
Synthesis and Tranquillizing Effect of New 1,4-Benzoxazepines. Egyptian Journal of Chemistry, 2011; 54(4): 565-578. doi: 10.21608/ejchem.2011.1411