A Novel Triacylglycerol from A Cytotoxic Extract of A Red Sea Marine Fungus

Abstract

 INVESTIGATION of the CH2Cl2 extract of a taxonomically …….unidentified anamorphic fungus strain MF 014, has yielded the glycerol triester, 1,3-O-bis-Z-11-eicosenoyl 2-O-Z -9, Z -12-nonadecadienoyl glycerol. The structure of this novel metabolite was established on the basis of extensive 1D- and 2D-NMR spectroscopic studies as well as on mass spectrometric analysis. The extract exhibited in vitro cytotoxic activity against human amniotic epithelial cells (FL cells) in the neutral red assay.

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