Fate of 14C-ethyl Profenofos in Soybean Seeds and Oils, Residue Removal, Bioavailability, Toxicity and Protective Action of Cinnamon Extract towards Experimental Animals

doi:10.21608/ejchem.2011.1386

Fate of 14C-ethyl Profenofos in Soybean Seeds and Oils, Residue Removal, Bioavailability, Toxicity and Protective Action of Cinnamon Extract towards Experimental Animals

10.21608/ejchem.2011.1386

Abstract

THE TOPICAL application of 14C- profenofos on soybean plant ..... led to the appearance of 10 ppm 14C-residues in the dry seeds at harvest time. Commercial processing procedures led to a gradual decrease in the total amount of 14C-residues in oils. The complete refined oil from treated seeds lost about 80% of the total 14C-residues. The major part of 14C-residues after feeding rats with the extracted soybean seeds for 72 hr was eliminated via expired air (45%) while radioactivity in urine and feces accounted for 18% and 12% of the taken 14C- residues, respectively. The results revealed that profenofos residues induced abnormal hepatic and renal function which was remarkably attenuated with co-administration of water extract of cinnamon powder thereby suppressed the deviation in the liver and kidney function markers. From the present investigation it can be concluded that the used plant extract exerted prophylactic beneficial action against profenofos induced hepatic and renal damage via its antioxdating potential effects.

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