3- (4-AMINOPHENYL)-2-benzyl-4-oxo-3,4-dihydroquinazoline 1a and 3 - (4 - aminophenyl) - 2 - benzyl - 6 - bromo - 4 - oxo -3, 4 dihydroquinazoline 1b were prepared and diazotized by nitrous acid to give ″2a, b″. The diazonium chloride derivatives were converted to the corresponding 3-arylhydrazono derivatives on treatment with active methylene compounds namely acetylacetone, ethyl acetoacetate and/or ethyl cyanoacetate. The hydrazono derivatives were converted to the corresponding pyrimidino derivatives ″6a-f″, pyrazolo derivatives ″7a-d″ and pyrazoline derivatives ″8a-d″ and ″9a-f″ in order to study their antimicrobial activity. A significant level of activity of the new products was observed.
(2011). Synthesis and Biological Activity of Some New Substituted Quinazolin-4(3H)-Ones. Egyptian Journal of Chemistry, 54(1), 1-15. doi: 10.21608/ejchem.2011.1376
MLA
. "Synthesis and Biological Activity of Some New Substituted Quinazolin-4(3H)-Ones". Egyptian Journal of Chemistry, 54, 1, 2011, 1-15. doi: 10.21608/ejchem.2011.1376
HARVARD
(2011). 'Synthesis and Biological Activity of Some New Substituted Quinazolin-4(3H)-Ones', Egyptian Journal of Chemistry, 54(1), pp. 1-15. doi: 10.21608/ejchem.2011.1376
VANCOUVER
Synthesis and Biological Activity of Some New Substituted Quinazolin-4(3H)-Ones. Egyptian Journal of Chemistry, 2011; 54(1): 1-15. doi: 10.21608/ejchem.2011.1376
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