Novel Synthesis of Fused Pyrazolopyrimidines and C-Nucleosides of Thienopyrimidone with Expected Antimicrobial Activity

Abstract

 
STARTING from thienopyrimidine hydrazine derivatives (1a,d) and (2b,c) a series of pyrazolopyrimidine derivatives has been synthesized. Also, some acyclic and cyclic C- nucleosides of thienopyrimidone (7-10) were prepared by treating compound 1a with aldoses. The prepared products showed antimicrobial activity. Structures of the new compounds were elucidated on the basis of their elemental analyses and spectral data.

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