2024-03-29T06:59:19Z
https://ejchem.journals.ekb.eg/?_action=export&rf=summon&issue=21851
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Enhancement of The Dielectric and Nonlinear Optical Properties of PbSe Nanomaterial Thin Films with Different Contents of Polyethylene Glycol
Samia A.
Gad
Ahmed
Abdel Moez
Gehan M.
Mahmoud
Fatma S.
Terra
PbSe nanocrystals doped with poly ethyleneglycol (PEG) were prepared using hydrothermal method. The reflectance spectra (R) were measured for these samples, and also refractive index (n) values were calculated, which increase with PEG ratio. Both of (Ed) and (Eo) increase with PEG content, while (N/m*) ratio decreased with PEG content. While all of (M-1), (M-3) and static refractive index (no), were determined. (ε\) and (ε\\) peak position decrease with photon energy (hν). Also both of (σ1) and (σ2) decrease with (hν), while (χ(1)) increases with (hν) for all samples. The nonlinear optical parameters such as, (n2) and (χ(3)) decrease with PEG, as a result of increasing the sample density with PEG. (βc), were determined theoretically. Both electrical susceptibility (χ(e)) and relative permittivity (ε(r)) has blue shift with (hν) for all samples. (Nc/ m*e (cm-3)), (Nv/m*h (cm-3)) were calculated theoretically.
PbSe nanocrystals with different PEG contents
optical conductivity
Dielectric properties
nonlinear optical properties
semiconducting properties
2021
03
01
1101
1107
https://ejchem.journals.ekb.eg/article_139936_d4c135c212e46369a04b318f31cc760f.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Influence of Gamma Radiation on Nonlinear Optical, Semiconducting and Dielectrical Properties of In0.95Mn0.05Se Thin Films
Ahmed
Abdel Moez
Samia A.
Gad
In0.95Mn0.05Se films with of thickness 750 nm were evaporated by using thermal evaporation technique, this film was irradiated by γ radiation with doses (0,40 and 120 KGy). Both of dispersion energy (Ed) and oscillating energy (Eo) were determined. The values of lattice dielectric constant (εL) and free carrier concentration/effective mass) (N/m*) were calculated. On the other hand, the values of first order of moment (M-1), the third order of moment (M-3) and static refractive index (no), were determined. Both of dielectric loss (ε\) and dielectric tangent loss (ε\\) for these films increased with photon energy (hν). Also, the same behavior was noticed for the real part of optical conductivity (σ1) and imaginary part of optical conductivity (σ2). The Linear optical susceptibility (χ(1)) increases with (hν)for all compositions. The nonlinear optical parameters such as, nonlinear refractive index (n2), the third-order nonlinear optical susceptibility (χ(3)), non-linear absorption coefficient (βc) , were determined theoretically. Both of the electrical susceptibility (χe) and relative permittivity (εr) increase with photon energy and had a highest value near the energy gap. The semiconducting results such as, density of the valence band, conduction band and Fermi level position (Ef) were calculated.
In1-xMnxSe thin films
γ radiation
Dielectrical results
Semiconducting results
non- linear optical properties
2021
03
01
1109
1115
https://ejchem.journals.ekb.eg/article_139937_03a7033d2021a90f3809dcffdf29d7f9.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: First principles investigation of electronic properties of graphene doped with Al and N atoms
Elham A.
Mohamed
Afnan Z.
Mohamed
Fadl M.
Abou El-Ela
Samy H.
Aly
The geometry optimizations and electronic structure calculations were performed for graphene sheet doped with aluminium (Al) and nitrogen (N). The effect of doping has been examined by changing the concentrations of dopants from 2 % (one atom of the dopant in 50 host atoms) to 12 % (six dopant atoms in 50 host atoms). All the calculations have been performed by using the Burai Graphical user interface that used the Quantum Espresso code based on density functional theory, plane waves, and pseudo potentials. By Al and N doping, p-type and n-type doping are induced respectively in the graphene sheet. The results showed that the planar structure of the graphene sheet remains unaffected on doping. However, the electronic properties were changed from semimetal to semiconductor with an increasing number of dopants. These interesting results provide the possibility of tuning the bandgap of graphene as required and therefore extend its application in electronic devices.
Graphene
Graphene derivatives
DFT
Electronic properties
Band gap energy
Density of states
2021
03
01
1117
1123
https://ejchem.journals.ekb.eg/article_139938_221be71ca5fbad7dc25dd2585bef6f2d.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Dielectric Relaxation Behaviour and AC Electrical Conductivity of Cellulose Acetate-Molybdenum Trioxide Nanoparticle Blended Film
Dina
Ezzat
Mortada
Youssif
Hanan
Elhaes
Mahmoud
El-Nahass
Cellulose acetate (CA) and CA blended with molybdenum trioxide MoO3 nanoparticle at concentration of (0.0, 0.25, 0.5& 1.0 wt. %) prepared by casting method. Ac conductivity and dielectric properties were studied. Our results indicated that the conduction mechanism of CA and CA blended with different concentration of MoO3 nanoparticle is controlled by the correlation barrier hopping (CBH) model. The ac conductivity was observed to increase by adding MoO3 nanoparticle which explained by the network formed as the nanoparticle gets closer to each other as the concentration increase. The maximum barrier height was calculated and found to decrease by increasing MoO3 nanoparticle from 0.15 t0 0.12 eV. The analysis of the dielectric constant and dielectric loss suggested that their behavior can be explained by Maxwell–Wagner–Sillar type polarization at high frequency. At low frequency the polarization is high as a result of interfacial polarization. Arrhenius equation was used to calculate the activation energy of relaxation which found to decrease by increasing MoO3 nanoparticle.
Cellulose Acetate
MoO3
AC conductivity
Nanoparticle
Dielectric properties
2021
03
01
1125
1132
https://ejchem.journals.ekb.eg/article_139940_e6785f4d2aaff282bbc9bd0565247ad7.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Metal−organic Frameworks for Hydrogen Storage: Theoretical Prospective
Lobna A.
Heikal
Walid M.I.
Hassan
Asmaa S.
Hamouda
Hamdy F. M.
Mohamed
Ahmed H.
El-shazly
Medhat A.
Ibrahim
The adsorption of H2 in dehydrated and hydrated Materials of Institute Lavoisier (MIL-101) was investigated theoretically. The effect of terminal water molecules on adsorption as one of the more vital MIL-n trivalent chromium-based porous carboxylates in metal-organic frameworks application in the renewable energy field was also theoretically studied. The MIL-101 structures were optimized for geometry and energy minimization was performed. The calculations were carried out using density functional theory approach with B3LYP functional and mixed basis set of Lanl2DZ and 6-31G(d, p) for Cr and light atoms (C, H, O, F), respectively, as implemented in the Gaussian 09 program package. The spin and atomic charges distribution on the Cr metal atoms, adsorbate, and water molecules are calculated using natural bond orbital (NBO). The density of states (DOS) for the clusters was obtained using Gaussian smearing of Kohn–Sham orbital energies. The natural bond orbital (NBO) for molecular orbital analysis and atomic charge calculations were utilized. For the dehydrated MIL-101, more adsorbate molecules were found near the exposed Cr2 sites than the fluorine saturated Cr1 sites. Furthermore, terminal water molecules in the hydrated MIL-101 made more interaction sites and enhanced adsorption.
Metal-organic frameworks
Mil 101
Hydrogen storage
DFT
Adsorption energy
2021
03
01
1133
1140
https://ejchem.journals.ekb.eg/article_139941_d98daa88d5995d0ab9e6b49f8bc70aac.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Influences the Addition of Neodymium Oxide on Structural and Optical Properties of Oxyfluoride Lead Borate Glass
Ismail
Kashif
Asmaa
Ratep
The rare-earth-doped glasses have a great significance for promise applications in optical devices and laser technology. The glass samples prepared by melt quenching technique. XRD, FTIR, UV/VIS/NIR spectrophotometer and photoluminesces used to study the structure and properties of the glass samples. And found that the glass samples in the amorphous, the lead oxide enters the glass network as a former, analysis of splitting of Nd3+ in glasses, UV—Vis—IR spectra exhibit ten prominent bands centered at 428, 457, 471, 511, 524, 582, 624, 679, 744, 803 and 875 nm correspond to the transition from the ground state 4I9/2 to 2P1/2, 4G11/2, 2D3/2+2G9/2+2P3/2, 4G9/2, 2K13/2+4G7/2, 4G5/2+2G7/2, 2H11/2, 4F9/2, 4S3/2+4F7/2, 4F5/2+2H9/2, and 4F3/2 respectively. The Judd–Ofelt intensity parameters Ωλ (λ=2, 4, 6) determined from the absorption bands intensities of as Ω6>Ω4>Ω2. The emission peak intensity at 625 nm decreases with the Nd3+ concentrations increase due to the quenching effect.
Lead Oxyfluoride borate glass
XRD technique
DTA technique
FTIR Spectroscopy
density
Optical properties absorption and emission
2021
03
01
1141
1147
https://ejchem.journals.ekb.eg/article_139942_82e8b213fcf051debe55588a77436487.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Molecular Modeling Analyses of Polyvinyl Alcohol/ Sodium Alginate/ZnO Composite
Ahmed
Fahmy
Rasha M.
Khafagy
Hanan
Elhaes
Medhat A.
Ibrahim
Molecular modeling analyses based on density functional theory (DFT) is considered as a promising tool for elucidating different properties of polymeric materials on the molecular scale. So that, the electronic properties of polyvinyl alcohol (PVA)/sodium alginate (Na Alg)/ zinc oxide (ZnO) are conducted with B3LYP/6-311g (d,p) level. Some physical parameters like total dipole moment (TDM), HOMO/LUMO band gap energy, molecular electrostatic potential (MESP), quantitative structure activity relationship (QSAR) and finally some thermal descriptors are calculated. The obtained results of TDM and HOMO/LUMO band gap energies dedicated that a considerable change occurred in the electronic structure of the studied models. Also, molecular electrostatic potential results confirmed the results of TDM and HOMO/LUMO energy gaps. Meanwhile, the calculated QSAR and thermal descriptors ensure the results obtained by DFT calculations whereas their values reflecting higher reactive structures. This verifies the impact of modifying the proposed polymer blend with nano ZnO according to its unique physical and electronic characteristics in nano scale.
DFT
PVA
Na Alg
ZnO
QSAR
Thermal parameters
2021
03
01
1149
1166
https://ejchem.journals.ekb.eg/article_139943_628df075db4bdd1487e3a2ff9ac756a7.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Assessment of Heavy Metals Content in The Agricultural Soils of Kafr El-Zayat Egypt Using Laser Ablation Inductively Coupled Plasma Mass Spectrometry and Inductively Coupled Plasma Optical Emission Spectroscopy
Asmaa F.
Mankoula
Walid
Tawfik
Joel E.
Gagnon
Brian J.
Fryer
F.
El-Mekawy
Mohamed E.
Shaheen
Recent years have witnessed a tremendous increase in contamination levels of heavy metals in the agricultural soils due to the uncontrolled release of chemicals and toxic substances from various human activities. The transfer of heavy metals to the groundwater and humans through the various food chains may cause serious health problems. Therefore, continuous evaluation of heavy metals content in the agricultural soil is important to control the spread of pollution, to preserve the soil quality, and to protect human health. In this study, we determined the content of heavy metals (V, Cr, Mn, Co, Ni, Cu, Zn, and Pb) in the agricultural soils of Kafr El-Zayat city, Egypt using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and inductively coupled plasma optical emission spectroscopy (ICP-OES). In ICP-OES, the soil samples were digested using a mixture of concentrated nitric and hydrochloric acids at a ratio of 1: 3 and heating on a hot plate at a temperature of 120 ℃ for few hours. This method of sample preparation was not efficient in extracting the total metal content in the soils and the results had to be corrected for using reference materials. In LA-ICP-MS, the soil samples were prepared in a form of rigid pellets using a hydraulic press. The accuracy of the analyses was examined by analyzing reference materials and comparing the observed results to the published concentration values. The concentrations of heavy metals determined by the ICP-OES were found to be 90.14 ppm for Zn, 57.90 ppm for Cu, 75.3 ppm for Ni, 115.18 ppm for Cr, 32.75 ppm for Co, and 11.49 ppm for Pb. Meanwhile, the concentrations of heavy metals as measured by LA-ICP-MS were found to be 100.60 ppm for Zn, 69.78 ppm for Cu, 90.8 ppm for Ni, 116.42 ppm for Cr, 41.38 ppm for Co, and 18.24 ppm for Pb. The concentrations of V, Cr, and Ni exceeded the concentration levels of the Canadian soil quality guidelines, which indicate the contamination of the examined agricultural soils with these elements
Thermal parameters Agricultural Soils
heavy metal
Kafr El-Zayat
LA-ICP-MS
ICP-OES
2021
03
01
1167
1177
https://ejchem.journals.ekb.eg/article_139944_0a65dbd0140a9a2388ecf1fdac591e4f.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Gamma-rays interactions on the spectral properties of CuO-doped lithium host barium borate glasses
Mohamed. M.
Ibrahim
Hatem A.
ElBatal
Amr M.
Abdelghany
Mona. A.
Fanny
Mohammed Y.
Hassaan
Glass samples of undoped and CuO-doped barium borate host glasses were prepared. Combined optical properties together with structural FTIR spectral analysis were measured before and after gamma irradiation with a dose of 6 M rad. The optical spectral absorption of the base is characterized by prominent ultraviolet band which is correlated with trace ferric ions present as impurities. The CuO-doped glasses exhibit an extended broad visible –near IR band which is assumed to originate from octahedrally coordinated Cu2+ ions revealing obvious separation to two component peaks. The irradiation process is accompanied by an increase of the intensities of the absorption bands and can be attributed to proposed photochemical reactions between liberated electrons and formed positive holes with trace iron impurities. FTIR spectra reveal distinct two characteristic broad bands within the mid region 800-1200 cm-1 and 1200-1600 cm-1 indicating the presence of both tetrahedral borate groups and co-presence of triangular borate groups and the intensities of these two IR broad bands increase with the CuO content due to suggested polymerization of the borate network or changes in the ratio of BO4 and BO3 groups.
Barium borate glass
Gamma Irradiation
UV/Vis
FTIR
CuO
2021
03
01
1179
1185
https://ejchem.journals.ekb.eg/article_139945_a0cc5dbf87f9fc1a3f93dae02bb353dd.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Computational DFT Study of Gold Containing PVP/PEO/Gold Organometallic Polymer Nanocomposites
A.M.
Abdelghany
M. I.
Youssif
E.M.
Abdelrazek
D.S.
Rashad
Polyethylene oxide (PEO) and polyvinyl pyrrolidone (PVP) were used to prepare virgin and equimass fraction blend samples via an ordinary solution casting route. Polyblend was filled with a different mass fraction of green biosynthesized metallic gold nanoparticles (AuNP’s). The organometallic Nanocomposites were then studied using different characterization techniques. X-ray diffraction (XRD) investigation supports the formation of a face-centered cubic (FCC) structure of AuNP’s. FTIR spectral data reveals the persistence of the main vibrational groups in the polymeric matrix and suggests that the complexation process occurs via the carbonyl group. UV/Vis. is measurement used to estimate values of the optical energy gap and confirms the formation of AuNP’s in the nano-scale through observation of the surface plasmon resonance (SPR) peak at about 562 nm. Density functional theory (DFT) studies were employed to confirm the suggested mechanism of complexation between constituting polymers and to retrace structural changes within the polymeric matrices. Zeta sizer and transmission electron microscopy (TEM) reveals that AuNP’s were polydispersed with sizes ranging from 5-23.1 nm.
PEO
PVP
AuNP’s
DFT
FTIR
UV-Vis
TEM
2021
03
01
1187
1195
https://ejchem.journals.ekb.eg/article_139947_78f4079da1c1377c7743522545d45798.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Application of Cs/ZnO/GO Hybrid Nanocomposite for Enhanced Inter-behavior of Electronic Properties and Thermal Stability as Corrosion Inhibitor
Hend A.
Ezzat
Maroof A.
Hegazy
Nadra A.
Nada
Osama
Osman
Medhat A.
Ibrahim
Polymer hybrid nanocomposites are considered to be one of the most promising materials which in turn acquires new, multiple and improved properties such as optical properties and electrical conductivity used for various applications in the fields of optical integrated circuits, sensors, adhesives, coatings and corrosion inhibitors for metal protection. At the present time graphene oxide hybridization with metal oxide modified carbohydrate polymers performance for corrosion inhibition for metal. Hybrid nanocomposite Cs/ZnO/GO was considered to be studied by DFT theory. The considered Cs/ZnO/GO model structure were studied in the two interaction states once as adsorb state and once as complex state. Hybrid nanocomposite electronic properties and thermal stability in all designated states have been evaluated. B3LYP/LANL2DZ was used to calculate TDM, HOMO/LUMO band gap energy and MESP for hybrid Cs/ZnO/GO nano composite assumptions. Additionally, QSAR descriptors for thermal stability study were also calculated for the same interactions. The most certainly stable structure of the hybrid nanocomposite Cs/ZnO/GO was found to occur through OH of the carboxyl group COOH of GO in complex mechanism and through O of the carboxyl group COOH of GO in adsorb mechanism. It is also found that the structure Cs/ZnO/GO occurs by O of the carboxyl group COOH of GO in adsorb mechanism has a significant improvement in electronic properties and thermal stability with band gap 0.1750 eV that it could be used as Corrosion Inhibitor.
Chitosan
graphene oxide
ZnO
Hybrid nanocomposites
MESP
QSAR
2021
03
01
1197
1205
https://ejchem.journals.ekb.eg/article_139949_6ef3f4c55b744fa1e2e3f693e043fca0.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Synthesis and Characterization of ZnO Nanoparticles in Presence of Triethanolamine (TEA) as Surfactant Via Sol-Gel
Maroof A.
Hegazy
Hayat H.
El-Agamy
Zinc oxide (ZnO) nanoparticles have a great interest due to their important electrical and optical properties that have the potential to bring benefits to many areas of research and application. The present study is the preparation of zinc oxide nanoparticles using Sol–gel chemical method and the preparation using surfactant. The surfactant used was triethanolamine (TEA). Surfactant and unsurfactant ZnO nanoparticles were prepared to accomplish a comparative study. the properties of the prepared ZnO NPs have been characterized with the aid of many analytical techniques including Transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and UV–Vis spectroscopy. The surfactant used was triethanolamine (TEA). The obtained ZnO NPs were spherical with average size of 79 nm without agglomeration. FTIR spectra showed the adsorption of TEA on the ZnO surface. The results of the UV-vis studies showed a decrease in band gap energy of 2.23eV as compared with the unsurfactant value of ZnO (3.28eV). Surfactant ZnO nanoparticles showed larger crystallite size and smaller bandgap in contrast to unsurfactant ZnO nanoparticles. TEA can use for prepare of nanomaterials with different properties for specific applications.
Zinc Oxide nanoparticle
Triethanolamine (TEA)
sol-gel
Surfactant
band gap
2021
03
01
1207
1212
https://ejchem.journals.ekb.eg/article_139950_4236d95e45947a09eb3b24073830b26f.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Comparative Study on Copper Oxide Nanocrystals Synthesized by Two Precipitation Methods
Maroof A.
Hegazy
Hayat H.
El-Agamy
Copper oxide (CuO) nanostructures have attracted a lot of interest in recent years due to their interesting properties. In this study, preparation CuO nanostructures through the chemical reduction of copper sulfate with acetic acid. In our synthesis route, starch was added and worked both as a size and shape controller. The synthesized nanostructures were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and transmittance electron microscope (TEM). The average particle diameters were determined by the Debye-Scherrer equation and Analysis by Thermogravimetric analysis (TGA), BET.
Nano copper oxide
Starch
precipitation method
acetic acid
2021
03
01
1213
1217
https://ejchem.journals.ekb.eg/article_139951_249aca12d4b2240bd49461d67ee78b76.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS-2: Zinc Oxide nano-rods: Challenges for Glucose Biosensors
Hanan A.
Wahab
Aziza A.
El Saeid
Aida A.
Salama
Inas K.
Battisha
Zinc oxide nano-rod thin films (ZNR) will be deposited on silicon substrate (ZNRS) and borosilicate glass capillary tube tip (0.5 and 0.7 µm as inner and outer diameters, respectively) (ZNRT) using both Sol-Gel (SG) and aqueous chemical growth (ACG) techniques for glucose biosensor fabrication. It will be functionalized with membranes or enzymes to produce selective glucose biosensor for glucose concentration measurements in extracellular solutions. The prepared thin film samples provided a favourable environment for the glucose oxidase (GOD) immobilization and introduced a shuttling way for electronic communication between electrodes and GOD. The prepared ZNRS and ZNRT structures and morphologies will be characterized by X-ray diffraction (XRD) and Field emission high resolution scanning electron microscopy (FESEM).
ZNRS
ZNRT
sol-gel
Glucose biosensors
2021
03
01
1219
1227
https://ejchem.journals.ekb.eg/article_139952_542e16a17efbcaa71e0ae56da50d844f.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
ICMMS2: Molecular Modeling Study for Graphene modified with CH3, COOH, NH2 and O2
Aya A.
Mohamed
Lobna
Salah
Medhat A.
Ibrahim
A model molecule was built of graphene consists of 50 carbon atoms, after that was modified throughout its middle and corners with CH3, COOH, NH2 and O2 forming 20 model molecules respectively. Each model was then calculated at density functional theory DFT:B3LYP/6-31G(d,p). Results indicated that, the studied physical properties suffer strong changes in TDM and ∆E for the different position of the interaction. The interaction of graphene with CH3 and NH2 becomes more reactive for the connection at the center position where it shows highest TDM and lowest ∆E. COOH shows the highest TDM when interact with graphene at position1 and the lowest ∆E when interact with graphene at position2. While the reactivity of the interaction of graphene with O2 increased at position 2. Form the MESP calculation, it is clear that, the negativity increased by interaction of graphene with O2 at the corner in position one and four.
Graphene
Two-dimensional materials
TDM
HOMO/LUMO band gap energy
DFT
2021
03
01
1229
1238
https://ejchem.journals.ekb.eg/article_139953_503148d64294a5f7b9fc028f29827523.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Nuclear polyhedrosis virus DNA identification and first evaluation against Strawberry pest, Pentodon algerinum (Coleoptera: Scarabaeidae)
Samah
Abd EL-Aziz
Magda, H.
Rady
Bouthina, A.
Merdan
Hany, M.
Hussein
El-Sayed, M.A.
El-Saiedy
Abd El-Salam
A.M.E
In Egypt, The white grub, Pentodon algerinum (Coleoptera: Scarabaeidae) damages various economic important plants recently strawberry. This study aimed to DNA identification and first evaluation of the Spodopteda littoralis Nuclear polyhedrosis virus (SpliNPV) and Pentodon algerinum Nuclear polyhedrosis virus (PNPV) against Pentodon algerinum third instar larvae in the laboratory to find successful safe alternative control method against this pest. Bioassay was made by two experiments, one used five SpliNPV concentrations, 6.7X106, 3.11X107, 1.1X108, 3.64X109 and 3.64X1010 Polyhedral inclusion bodies (PIB/ml) achieved 80, 100, 100, 80 & 90% mortality respectively during thirteen days. Another experiment used four PNPV concentrations, 8.2x107, 8.2x 108, 2.6x109 and 8.2x109 PIB/ml caused 100, 70, 67 & 72.7% mortality respectively during ten days. SpliNPV Lethal concentrations LC50 6.2x1014 & LC90 8.9x109 PIB/ml were more than PNPV LC50 2.8X109 & LC90 1.8X108 PIB/ml. Thus PNPV and SpliNPV were effective against Pentodon larvae but PNPV was effective and specific more than SpliNPV. DNA of SpliNPV and PNPV was identified by RAPD PCR using four RAPD primers, Operon A9, A20, B17 & B7 (Operon Technologies, Inc., Alameda, CA, USA) using automated (Bio Rad, USA) thermal cycler. Total 33 bands were produced including 24 PNPV bands with molecular weights between 152-1204 base pairs (bp) included between resulted 9 SpliNPV bands having molecular weights between 138 - 1767 bp. Therefore PNPV is similar to SpliNPV in almost its DNA sites and also is a polymorphic copy from SpliNPV. Thus PNPV and SpliNPV can be recommended against this pest.
the white grubs
Pentodon algerinum
larval stage
Strawberry plants
RAPD PCR
SpliNPV
PNPV
2021
03
01
1239
1255
https://ejchem.journals.ekb.eg/article_147233_92cbfefe01a5dbcab32969b8c93d893d.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Metal-Organic Frameworks, a New Playground for Clean Energy and Environment
Hassan
Abdel-Gawad
Reda
Abdelhameed
As a class of versatile porous materials, MOFs have shown enormous potential for adsorption for environmental remediation and fuel purification. To efficiently remove harmful gases, it is not sufficient to use MOFs of the appropriate size/shape of the pores, and other more specific interactions between harmful adsorbents and the host are desirable. Most of the harmful gases are highly reactive. The adsorption of these gases often degrades the porous structures of MOFs. However, much progress has been made in the last few years to develop very persistent organic frameworks. Certainly more and more fundamental studies will appear in this direction, which should enhance the practical application of this type of new porous material for air purification and related fields in the future. MOFs contain multiple functional groups, conjugate bonds, and metal ions that can help for understanding the interactions between MOFs and pollutants and hense increase the adsorption efficiency. MOFs suffering from relatively poor water stability and reuse potential except for some types of MOFs such as MIL, UiO and ZIF are relatively stable in water. The big challenge is converting unstable MOFs in water to stable MOFs; this will lead to high recovery and extend its application.
Metal-organic frameworks
Synthesis
Removal
Harmful gases
organic pollutants
2021
03
01
1257
1271
https://ejchem.journals.ekb.eg/article_140622_23cb6a0dc015edc54a7db813af9792be.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Synthesis, Characterization and Biological activity study for new hybrid polymers by grafting 1,3,4-triazole and 1,2,4-oxadiazle moieties onto polyvinyl chloride
Mohanad
Kareem
Nour
Abdalrazzak
saadon
Aowda
Nagham
Aljamali
In this work 1,2,4-Triazole and 1,3,4-Oxadiazole derivatives were synthesized from [4-(4-hydroxy-3-methyl naphthyl) diazenyl] benzoic acid [M1], which were converted to [4-(4-hydroxy-3-methyl naphthyl)diazenyl] benzoate [M2]. Benzoate derivative reacted with hydrazine afforded [M3] which cyclized by carbon disulfide to give compound [M4]. In addition, cyclization of compound [M3] was accomplished by sodium hydroxide and thiosemicarbazide to give triazole- thiol [M5]. Hybrid polymers [M6 and M7] were synthesized by grafted 1,3,4-oxadiazole [M4], and 1,2,4-triazole [M5] onto the polyvinyl chloride in the presence of pyridine and tetrahydrofuran. These compounds were characterized by the following techniques: FT-IR, and 1H, 13C NMR spectroscopies, and elemental analysis C,H,N,S. The biological activity study, IC50 value was significantly decreased in M6 (IC50=25.76 µM/ml) and M7 (IC50=21.41 µM/ml). In addition, the biological activity for final products achieved with good results.
Naphthol
Azo dyes
Oxadiazole
triazole
PVC
Cytotoxicity
Anti-bacterial
2021
03
01
1273
1283
https://ejchem.journals.ekb.eg/article_148303_bcdc517c04630be24edaf1dcf27b2e23.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Study of Eco-Friendly Corrosion Inhibition for Mild Steel in Acidic Environment
Ashraf
Ashmawy
M.
Mostfa
The inhibition effect of Chamaemelum Nobile extract on corrosion of mild steel electrode in 1.0 molar hydrochloric acid was studied using gravimetric analysis and electrochemical methods. Results from the experimental studies have shown that, as the inhibitor concentration increases the inhibition efficiency. The adsorption of the inhibitor molecules on mild steel surface obeys Langmuir adsorption isotherm. Scanning electron microscope performed a surface study with and without inhibitors for mild steel. From all the results in this research, we found that Chamaemelum Nobile extract was an attractive alternative to prevent corrosion as it shows the great inhibition efficiency.
Corrosion inhibition
CNE
Mild steel and hydrochloric acid
2021
03
01
1285
1291
https://ejchem.journals.ekb.eg/article_126519_063e90e1c1a5a65e017fd833f48db253.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Sugarcane Bagasse Biochar with Nanomagnetite: A novel Composite Heavy Metals Pollutants Removal
Ola M.
Abd Almawgood
Sayed A.
El Tohamy
Eman H.
Ismail
Farag A.
Samhan
Abstract In this novel, we developed a modern and efficient adsorbent that may serve as environmental protection and sustainable development for removing some metal ions such as Fe and Zn from aqueous solution. The new adsorbent was synthesized by mixing the sugarcane bassage biochar with nano-magnetite (SCB-BC/Fe3O4) to form nano-composite. High resolution transmission electron microscope (TEM) imaging shows the synthesized nano-composite with 40 nm average diameters. The adsorption kinetic of metals on the nano-composite was discussed, and the equilibrium equation of the metal ions was found following Langmuir isotherm model. The experimental data showed that the synthesized (SCB-BC/Fe3O4) nano-composite can quantitatively remove the metal ions from water by removal efficiencies of 90% and 96% for Fe and Zn respectively. It can be concluded that the synthesized adsorbent can be used for removal of heavy metals from water and/or wastewater as one of the treatment stages in treatment plants.
Nano-materials
Nano-composites
Wastewater treatment
Heavy Metals Removal
2021
03
01
1293
1313
https://ejchem.journals.ekb.eg/article_131521_bacbb384cfd37db7ddcc739f0d91f6d3.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Antioxidant and Antimicrobial Activities of Some Novel 2-Thiohydantoin Derivatives
Dakhil
Mutlaq
Ali
Al-Shawi
Layla
AbdulJabar
Four new 2-thiohydantoin derivatives (4a-d) were synthesized from the reaction of maleimide derivatives (3a-d) with phenylisothiocyanate. The structures of synthetic compounds were characterized using Fourier-transform infrared spectroscopy (FT-IR), 1H- and 13C-nuclear magnetic resonance (NMR) spectroscopy, and mass spectrometry. The antioxidant activity of the synthesized compounds showed inactive 4b and 4c compounds, moderately active 4a, and strongly active 4d, compared with vitamin C as positive control (IC50 values = 1.380, 1.726, 4.147, 8.085, and 9.826 µM, respectively). Antibacterial and antifungal activities of compounds showed that only compound 4b had an effect on Pseudomonas aeruginosa, Candida albicans, and Aspergillus niger species.
Bioactive heterocyclic compounds
2-thiohydantoin
antioxidant
Antibacterial
Antifungal
2021
03
01
1315
1321
https://ejchem.journals.ekb.eg/article_126737_3099c33fd7bec3821e83f1926f76f271.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Low Cost Ceramic Product Based on Mixing Granodiorite and Talc from Eastern Desert, Egypt.
Said
Abd El Rahim
Nahla
Abd El Ghaffar
Zeinab
Abd El-Shakour
Esmat
Hamzawy
The Abu Ziran area is easily accessible following the Quseir-Qift asphaltic road in the Central Eastern Desert of Egypt. Microscopically and geochemically, the granodiorite rock represents a good source for the major oxides that are contained in its mineral components: quartz, oligoclase, orthoclase, microcline, biotite and hornblende as its essential minerals; besides sphene, zircon, apatite and magnetite as its accessory minerals. These minerals represent suitable raw materials in the formulation of the low cost ceramic product. The low cost ceramic materials were prepared from mixing wastes of granodiorite and talc quaries in the Eastern Desert, Egypt. Four samples were prepared in the 70:30, 60:40, 50:50 and 40:60 ratios of granodiorite:talc. After sintering process of the green ceramic samples up to 1300 C, aluminum enstatite, kyanite, pyrope and cristobalite were developed. The microstructure of the sintered samples show rod-like crystals in micron and submicron size oriented or disoriented in glassy matrix. The samples enjoy good densities between 1.65 and 2.21 g/cm3 and porosity ratio between 18.01 and 39.27 %. This low cost ceramic product can be used in insulation for heat and sound.
Abu Ziran area
Egypt
Granodiorite
talc
Ceramic Product
insulation
2021
03
01
1323
1331
https://ejchem.journals.ekb.eg/article_125551_0252b26fb50c450e780cf84e04cde728.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Synthesis, Spectroscopic characterization and bactericidal valuation of some metal (II) complexes with new Tridentate Heterocyclic Azo Ligand Type (NNO) Donor
Ghusoon
Hameed
Fawzi
Wadday
Murtadha
Farhan
Sahar
Hussain
Abstract In this article, a synthesized ligand [(1-phenyl-2-pyrazolin-5-one) azo (6-bromo-2-hydroxynaphthalen-1-yl)] has employed for preparing three new complexes of Co(II), Ni(II) and Cu(II). The new azo ligand (PABH) has analyzed by Micro Elemental Analysis (CHNO), UV-visible, Fourier Transform infrared (FTIR) approaches, 1H,13C-NMR spectroscopy and mass spectroscopy. The consequence has specified that the ligand was represented as N,N,O-tridentate. The preparing of complexes has accomplished after fixing the finest concentration and pH values. UV-Vis spectra of these complexes solutions have been examined for a range of pH (5-9) and concentration (1×10-4 - 5×10-4) Molar that comply with Lambert-Beers law. A stoichiometry of the complexes has comprehended in relation to mole ratio which has investigated from a spectroscopic technique. The ratio of metal: ligand was achieved with (1:2) for all complexes. The metal ions complexes were characterized by FTIR, UV-Visible, molar conductance, atomic absorption, magnetic susceptibility and elemental analysis CHNO techniques. From the results of physico-chemical and spectral techniques, octahedral geometry has been proposed for these metal complexes. All these compounds were evaluated against two kinds of human pathogenic bacteria such as Staphylococcus aureus (Gram Positive) and Escherichia coli (Gram negative).
Spectral studies
complexes
Azo
antimicrobial activity
Mass Spectroscopy
2021
03
01
1333
1345
https://ejchem.journals.ekb.eg/article_131524_68d2188b574e38712146d642367fd69e.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
The Influence of Various Zirconia Contents on Crystallite Sizes, Shrinkage, and Physical and Mechanical Properties of Hydroxyapatite-Based Nanobiocomposites
Rasha
Abdel Hakam
Mohamed
Abdel Aziz Taha
Medhat
Ibrahim
Carbonated hydroxyapatite (CHA)-based nanocomposite powders with different zirconia (ZrO2) contents, up to 8 wt.%, were prepared using high-energy ball mill. Phase composition of the resultant nanocomposites was investigated by X-ray diffraction (XRD) technique. Moreover, the crystal size, lattice strain and dislocation density were calculated. In order to measure shrinkage, physical and mechanical properties of these nanocomposites, their powders have been consolidated and sintered at 1000 °C. The results revealed that the gradual increase in ZrO2 contents caused increase in the lattice strain and dislocation density. On the opposite side, their crystal sizes decreased with increasing ZrO2 content. Moreover, the mechanical properties including microhardness, compressive strength, Young's modulus, elastic modulus, bulk modulus, shear modulus and Poisson's ratio of the sintered nanocomposites were greatly improved with increased ZrO2 contents until they reached 7 GPa, 165 MPa, 57 GPa, 70 GPa, 47.5 GPa, 22 GPa and 0.267, respectively for the sample containing the highest ZrO2 content. However, in spite of the great importance of ZrO2 contents on the mechanical properties, they caused noticeable increases in the porosity of the sintered samples. Additionally, increasing of ZrO2 contents, up to 8 wt.%, reduced the shrinkage percentages from 12.3% to 9.5%.
Hydroxyapatite-based nanobiocomposites
Crystallite size
Shrinkage measurement
Physical properties
Mechanical Properties
2021
03
01
1347
1352
https://ejchem.journals.ekb.eg/article_139935_c9b86d23c3d8a6e981def2c4357edcc2.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Highly efficient capture of Th(IV) from aqueous solutions using GO/TiO2 nanocomposite
Eman
Kamal
Gehad
Abd El-Aziz Mohamed
Inas
El-Sabbagh
An adsorbent GO/TiO2 nanocomposite has been synthesized and characterized. FTIR, XRD, TGA, TEM, SEM and EDX were used to characterize the prepared composite. In a batch method, the adsorption properties of the prepared composite against thorium ions were examined. Th(IV) adsorption kinetics study on GO/TiO2 suggests that the adsorption equilibrium attained within 240 min and depends on the pH value. The adsorption results were expressed mathematically by using Langmuir and Freundlich sorption models. The nanocomposite showed the highest Th(IV) adsorption of 292.32 mg/g at pH 2.5 and 25 oC. The thermodynamic results indicated a thermodynamically favorable, random and exothermic nature of the adsorption process. The obtained results demonstrate that GO/TiO2 nanocomposite can be regarded as a fast, effective and convenient water-based adsorbent for adsorption of Th(IV). This study suggests that nanocomposite can be a promising candidate for the removal of Th(IV) from aqueous solution.
Nanocomposite
Thorium
graphene oxide
Titanium dioxide
Adsorption
2021
03
01
1353
1362
https://ejchem.journals.ekb.eg/article_128403_a80dfdec259b031fc9626058c7b3c2c1.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
A Simple Synthesis of Some Novel Bi-Thiazoles as Anti-Tumor Agents
Sami A.
Al-Hussain
Revised Abstract A series of novel bi-thiazoles was synthesized by reaction of 2-(1-(2-(2-(1-(4-fluorophenyl)ethylidene)hydrazinyl)-4-methylthiazol-5-yl)ethylidene) hydrazine-1-carbothioamide 3 with a variety of hydrazonoyl chloride derivatives 4a-d, and 7 a-d affording 6a-d and 9a-d respectively in dioxane in the presence of triethyl amine as a base. Also, hydrazine-1-carbothioamide 3 reacts with substituted phenacyl bromide derivatives 10 a-d yielding 12a-d in appropriate reaction conditions. The mechanisms of the titled reactions were discussed. Structural assignments were based on spectroscopic methods (NMR, FTIR, MS). The new compounds were tested in vitro for their were subjected to in vitro anticancer screening against human hepatocellular carcinoma (HCT-116), (HepG-2) and the results showed that compounds 6a, 6d, 9a, 9c and 12a have promising activities compared with cisplatin reference drug.
Heterocycles
Hydrazonoyl halides
cyclization
Hydrazones
bi-thiazoles
2021
03
01
1363
1370
https://ejchem.journals.ekb.eg/article_125554_f82564c02ac370de8fe40454abda4a1e.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Kinetic studies on the adsorption of uranium on a mesoporous impregnated activated carbon
Elsayed Aly
Haggag
mohamed
masod
ahmed
abdelsamad
mostafa
mohamed
Mohamed
ebiad
A highly porous phosphorous-containing activated carbon derived from pistachio nutshells (PNS) was synthesis as a potential sorbent for uranium (VI) from sulfate media. The prepared phosphate activated carbon (PAC) was visualized under SEM and TEM which revealed highly porous structure. The extraction of U(VI) from acidic media using PAC has been investigated by a batch method and various parameters such as pH, equilibrium contact time, liquid to solid ratio, and initial U(VI) concentration were examined. Under the stated conditions, the optimum pH for U(VI) adsorption was found to be 3.5. The adsorption capacity of uranium upon PAC under the optimum conditions was found to be 335 mg/g. The experimental results were applied for Langmuir, Freundlich, Temkin, and Dubinin-Radushkevich (D-R) isotherm models. The thermodynamic equilibrium constant and the Gibbs free energy were determined (ΔG° from -4.72 to -7.65 kJ/mol) and results indicated the spontaneous nature of the adsorption process. Kinetics data were best described by pseudo second-order model.
Pistachio nutshells
Uranium extraction
Highly acidic solution
Phosphorous-containing activated carbon
2021
03
01
1371
1385
https://ejchem.journals.ekb.eg/article_131160_c353813e2ae7b7de2b1b2e112b63ea69.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Chemical and Biological Activities of Deverra triradiata Hochst. ex. Boiss. Aerial parts from St.Catherine, Southern Sinai, Egypt.
Amani
Elmosallamy
Enas
Ibraheem
Mohamed
Sarhan
Sahar
Hussein
The present study describe the phenolic and flavonoid profiles of the ethyl acetate extract of D. triradiata which have been demonstrated by high-performance liquid chromatography (HPLC) to prove the presence of 15 compounds, nine major compounds namely, querectin (46.37 mg/g), vanillin (11.94),daidzein (10.02),ellagic acid (4.76), propyl gallate (3.89), naringenin (3.27), gallic Acid (3.18 mg/g), rutin (2.7) and chlorogenic Acid (2.58). The chemical constituents of unsaponifiable portion of petroleum ether 60-80o extract which analyzed by gas-liquid chromatography (GLC) proved the presence of 14 hydrocarbons and three sterol; n-eicosane (16.94%), n-docosane (8.22 %), n-heptadecane (7.13 %),squalene (6.89%), n-tricosane (1.63 %), n-hendecane (1.63 %), cholesterol (1.12 %), campesterol (3.81 %) and stigmasterol (5.27 %).The saponifiable portion five unsaturated fatty acids were indicated as,α-Linolenic acid (17.95 %), arachidonic acid (11.37), linolenic acid (6.12),oleic acid (3.36) and palmitoleic acid (3.01) and also four saturated fatty acid named by, palmitic acid (31.61), myristic acid (7.17), Lauric acid (1.67) and stearic acid (1.47).Total phenolic (tannic acid equivalent), total tannins (tannic acid equivalent) and total flavonoids (quercetin equivalent) were (67.8±0.39, 31.4 ± 0.63 and 4.7 ± 0.077 mg/g d.w.), respectively. The in vitro antioxidant activity using the stable free radical DPPH (2,2-diphenyl-1-pycrylhydrazyl) method of the petroleum ether and ethyl acetate extracts . The percentage of maximal inhibition for extracts in DPPH are 18.42 ± 0.39 and 43.58±0.52 %, respectively compared with percentage of gallic acid 91.29 ±0.72μg/ml, which proved that ethyl acetate extract possesses a distinct radical scavenging effect, which may be attributed to its high polyphenolic content.The in vitro cytotoxic activity by using SRB assay, of petroleum ether showed promising activity against (MCF7), (PC3) and (HCT 116) with IC50 18.8, 9.3 and 9.5 ug/ml, respectively, compared with normal cell. Baby Hamster kidney (BHK) with IC50 37, while, the ethyl acetate extract showed weak activity against (MCF7), (PC3) and (HCT) with IC50 42, 42 and 37 ug/ml, comparable to (BHK) normal cell with IC50 59 μg/ml. All identified phenolic compounds are therapeutically active compounds with anticancer potency and antioxidant capacities which were reported for the first time.
Deverra triradiata
HPLC
GC
Total phenolic
Flavonoids
antioxidant
Cytotoxicity
2021
03
01
1387
1394
https://ejchem.journals.ekb.eg/article_130405_b90494a0fbb4b38d85a2bc68fe894755.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Preparation and Characterization of Novel Zinc Aluminate NanoPowders Doped with Copper (II), Loaded and Non-loaded with Carbon Spheres Using Co- Precipitation Method and Its Environmental Application
mohamed
Zayed
Mohamed
Rashad
Diaa
Rayan
Shimaa
Aboueata
Due to rapid industrialization, the presence of heavy metals in water and wastewater is a matter of environmental concern. Though some of the metals are essential for our system but if present beyond their threshold limit value (TLV), they are harmful and their treatment prior to disposal becomes inevitable. The present communication has been addressed for the removal of Cr (VI) from aqueous solutions by synthesized zinc aluminate novel nano-materials doped with copper (II); loaded and non-loaded with carbon spheres (CSs) using the co-precipitation technology. The as-prepared precursors of Cu(x)Zn(1-x)Al2O4 were annealed at 1000 oC for 2 h. The characterization of the samples nanoparticles were implemented by X-ray fluorescence (XRF), X-ray diffraction (XRD), transmission electron microscopy (TEM) analysis, photoluminescence spectra (PL) as well as the optical properties was demonstrated by UV–visible–near IR spectrophotometer. The optical properties of the prepared nano-materials and their catalytic performances are well discussed. Batch experiments were adopted for the adsorption of Cr (VI) from its solutions. The effect of doped copper ions and Cu (II) / CSs co-dopants on the behavior of ZnAl2O4 on removal of chromium was studied using inductively coupled plasma (ICP) analysis that had been used to measure removed and remaining Cr (VI) from its water polluted samples.
Key Words: Zinc Aluminate
copper (II) and Cu (II)/CSs co-dopants
co-precipitation
Photoluminescence (PL)
Cr (VI) removal
2021
03
01
1395
1409
https://ejchem.journals.ekb.eg/article_129370_a7af5575dbe965127e670a7b2d4c40de.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Biocidal Activity of Polyester Fabrics Modified with SiO2 Nps
Lamiaa
El-Gabry
Nahed
Abd El-Ghany
Sara
Aboras
Amira
Abou El-Kheir
The inorganic nano-sized silicon dioxide modify polyester fabrics using IR dyeing machine was constructed. Chemical activation method with alkali hydrolysis of the fabric was done to facilitate the binding affinity of SiO2 NPs via carboxylic and hydroxyl groups created on the fabric surface. The morphological structure of the treated fabrics was investigated by field-emission scanning electron microscopy (FE-SEM). Dispersive X-ray spectroscopy (EDX) of the untreated and treated polyester fabrics was measured. Fourier transformed infrared spectroscopy (FTIR) of the untreated and treated fabrics was elucidated. TEM of the used silicon dioxide nano particles was monitored. Thermogravimetric analysis (TGA) and UV protection and of the treated fabrics were studied. Antimicrobial activity of finished polyester fabrics containing SiO2 NPs was tested against Gram-positive (Staphylococcus aureus), Gram-negative (Escherichia coli), and pathogenic fungi (Candida albicans and Aspergillus flavus). The results indicate that the nano-silica has an excellent effect on antimicrobial activity and good protection of both UVA and UVB even after ten washing cycles, indicating the excellent laundering durability. The performance of treated fibers to be used as medical textile was determined by radar chart area.
Polyester fabrics
Nano- silica
antimicrobial activity and UPF protection
Radar Chart
2021
03
01
1411
1419
https://ejchem.journals.ekb.eg/article_135686_9a07d75dd919cf61d6726a6e0f2057dd.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
CO2 Emissions, Green House Gas Calculations and Controlling in the Gas Plant
Ebrahiem
Ebrahiem
Abdelaziz
Noaman
Tarek
Aboulfotouh
Moustapha
Mansour
Yassin
Hakim
Gas flaring is one of the most challenging energy and environmental problems facing the world today whether regionally or globally. Gas flaring becomes a public concern and a priority issue because it’s waste of a non-renewable source in addition to environmental problems due to gas emissions that produce greenhouse effects. Also, it represents definite risks to human health. Air emissions calculations were conducted based on the international guidelines and found that CO2 pollutant is the main source of the emissions in the gas plant, the yearly emissions of CO2 are 343.3 Ton /year. The second source of emissions in the gas plant is CH4. The yearly emissions from methane CH4 is 3.3 Ton/year. The other sources of emissions in the gas plant include CO, NOx and VOC. Total GHG emissions from the gas project Facilities during normal operation are estimated to be 55,133 Ton/year CO2 equivalents. CO2 is the main GHG pollutant, which contributes over 91% of the GHG. The calculated GHG intensity of the gas project facilities is 0.05 Tons of CO2 equivalents per ton of the total production. To minimize the emissions and GHG in the process facilities of the gas plant waste heat recovery unit must be installed, Ultra-Low NOx Burners is recommended for minimizing NOx emissions, CO2 Gas injection to the reservoir to be installed and finally the energy efficiency of the project facilities should be improved by enhancing heat integration and recovery throughout the plant
Keyword: flared gas
emission
GHG
fired heater
CO2 injection
2021
03
01
1421
1431
https://ejchem.journals.ekb.eg/article_126522_6b8b0b2b2586d1657e9dee641c9fa36b.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Ultrasound-Assisted Extraction of Damsin and Neoambrosin from Ambrosia maritima: Optimization Using Response Surface Methodology
Shymaa
Ali Abdeldayem
Mohammed
Khalil
Enas
Abdelrahman
Hamida
El-Gohary
Ali
Yehia
Damsin and neoambrosin are two important anticancer phytopharmaceuticals of Ambrosia maritima (Damsissa). Despite their importance, no report has yet discussed their extraction from plants on lab or industrial scales. Consequently, the present article aims to develop an ultrasonic-assisted extraction (UAE) model for their extraction on the lab scale. Box-Behnken model was applied to investigate the effects of ethanol strength (X1: 40-100%), drug solvent ratio (DSR, X2: 1:20-1:60), and time (X3: 30-90 min) on the yield of damsin and neoambrosin in damsissa extract. Surprisingly, only ethanol strength was the significant factor in damsin yield with an optimum value of 65%. Time and DSR played no significant roles in damsin content. No statistically significant model could be deduced for neoambrosin. The model is a preliminary step to elucidate factors affecting the UAE of sesquiterpene lactones from plants and a preamble for its large scale green extraction.
Damsin
Neoambrosin
Ultrasonic-assisted extraction
response Surface method
sesquiterpene lactones
Ambrosia
2021
03
01
1433
1439
https://ejchem.journals.ekb.eg/article_128408_2f2e162b5582601704ab34e65b7cc879.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Kinetics and Mechanism of The Oxidation of 2-Methylindole by Alkaline Potassium Hexacyanoferrate(III)
Iqab
Amer
The reaction of 2-methylindole with hexacyanoferrate(III) in alkaline media to produce the corresponding 2-methylindolin-3-one has been studied at constant temperature and ionic strength. The reaction followed first order kinetics with respect to [2-methylindole], [OH-] and [Fe(CN)63-]. The effects of added electrolytes, potassium hexacyanoferrate(II), relative permitivity and temperature have also been studied. On the basis of experimental observations, a probable reaction mechanism has been proposed.
2-methylindole
hexacyanoferrate(III)
2-methylindolin-3-one
kinetics and oxidation
2021
03
01
1441
1446
https://ejchem.journals.ekb.eg/article_130402_86658abe462164fe5cf7d5ca74e5dda5.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Extracts of M. pulegium (L.) and M. spicata(L.): Effect of Extraction Conditions on Phenolics and Flavonoïds Contents and Their Antioxidant Power
Nadia
Zekri
Hannou
Zerkani
Hanane
Elazzouzi
Touria
Zair
Mohammed Alaoui
El Belghiti
The correlation between the contents of polyphenols and flavonoïds and the degree of antioxidant activity of various extracts from M. pulegium (L.) and M. spicata (L.), obtained by different solvents and methods, was investigated. The crude extracts were prepared by mixing areal parts in powder with methanol/water solution. They were subjected later to liquid-liquid extraction via solvents with progressive polarity (chloroform, ethyl acetate and n-butanol) by maceration and soxhlet techniques. The total phenol and flavonoïds contents from crude extracts and their fractions were determined by using Folin-Ciocalteu and AlCl3 assays respectively. The antioxidant activity of extracts was evaluated by DPPH• (1,1-Diphenyl-2-picrylhydrazyl) radical scavenging test. This activity was measured by inhibition concentration 50% (IC50) values. Generally, higher extract yields were obtained by the soxhlet extraction technique; the crude extracts recorded the best yields for M. pulegium by soxhlet (26.37%) and maceration (13%) while for M. spicata, the aqueous extract by soxhlet (34.9%) and crude one by maceration (9.4%) showed the higher yields. The higher phenolic and flavonoïds contents were found in crude extracts by maceration for both mints whereas by soxhlet, the ethyl acetate and/or n-butanol extracts demonstrated the strongest contents. These extracts, rich in flavonoïds, showed a positive correlation since they have exhibited better antioxidant activity compared to ascorbic acid as the antioxidant reference (IC50= 0.051 mg/ml).
Mentha
Polyphenols
Flavonoids
Extraction
DPPH˙test
2021
03
01
1447
1459
https://ejchem.journals.ekb.eg/article_129004_0686950a7d83beef05aa5c4f4baef27b.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Optimization of Banana Stem Pulp to Substitute SoftWood Pulp for High Quality Paper
Mamduh
Nassar
Ebrahim
Ebrahim
Hisham
Sherif
Mohamed
Ali
Abstract This study deals with optimizing pulping conditions of the banana stem to substitute softwood pulp in writing and printing paper. Scanning micrograph and chemical composition of banana stem indicate that banana fibers are flat, flexible, long (2.24 mm) and the raw banana is characterized with high cellulose (65%) and low lignin (13.5%)contents. The banana stem was pulped using Kraft process (8.5 % alkali as Na2O and 17% sulfidity cooked at 105oC for 3 hr. Detail mechanism of the pulping parameters was discussed. The obtained pulps were characterized with respect to yield (64%) and Kappa number (35%). Compared to imported softwood pulp, all strength properties and opacity are high. This is attributed to the long banana fibers and the high cellulose content. The effect of these two parameters on tensile, burst, and tear, strengths was discussed. High quality of writing and printing paper was obtained by a furnish blend ratio of 20%-80%, banana stem pulp, and commercial bagasse pulp respectively. Keywords: Banana Stem, Fiber length, Sulfate pulp, writing and printing papers.
: Banana Stem
Fiber length
Sulfate pulp
writing and printing papers
2021
03
01
1461
1469
https://ejchem.journals.ekb.eg/article_123805_b13847917d6598ddfb1b319908846722.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Ablation And Thermal Properties Of Ethylene Propylene Diene Rubber/Carbon Fiber Composites Cured By Ionizing Radiation For Heat Shielding Applications
Khaled F.
El-Nemr
Medhat M.
Hassan
Emad M.
Masoaud
Eman M.
Abdullah
Zohor A.
Hanko
In this study, new composites were prepared from ethylene propylene diene rubber (EPDM) that loaded with various concentrations of short carbon fibers (SCFs) ranged from 5 up to 20 part per hundred part of rubber (phr). Aluminum trihydroxide (ATH) was added by two concentrations, namely 10 and 30 phr to EPDM/SCFs composites to enhance its heat shielding. Foaming agent, azodicarbonamide (ADC) was added to increase ablation resistance. Composites were prepared on open rubber roll mills, and then the rubber composites were gamma ray irradiated at different doses of 25, 50, 75, 100 and 150 kGy. Fiber incorporation into rubber matrix has been proven as a key factor in enhancing tensile strength and flame retardant properties of fabricated composites. The prepared composites were characterized by using various analytical methods counting physico-mechanical properties, thermal gravimetric analysis (TGA), Ablation test (oxy acetylene test) and propagation flame test. The utmost mechanical performance was reported for the incorporated 5 phr of carbon fiber into EPDM at 100 kGy. Also, the flame retardancy and ablation properties for composites were enhanced by increasing addition of carbon fibers and ATH in presence of ADC.
Composite
Carbon fiber
Ethylene propylene dine rubber (EPDM)
Gamma radiation. Ablation test
2021
03
01
1471
1479
https://ejchem.journals.ekb.eg/article_128645_d3f1c520ca0404d2440eb5d8ecb75372.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Photocatalytic Degradation of Congo Red Dye via Multi-Walled Carbon Nanotubes Modified CuO and ZnO Nanoparticles under Visible Light Irradiation
Amal
Alkahlawy
Radwa
El-Salamony
Heba
Gobara
The photocatalytic degradation of congo red dye (CR) using nanocomposites materials of multi-walled carbon nanotubes combined with some transition metal oxide under visible light irradiation was studied. Multi-walled carbon nanotubes were prepared via chemical vapor synthesis (CVS) and loaded with some transition elements as Cu, Zn, and Cu0.1Zn0.9O nanoparticles, where the ratio of metal was kept constant in all catalysts (20% M). Various Characteristic techniques were adopted such as X-Ray Diffraction (XRD), Nitrogen adsorption-desorption, Transmission Electron Microscope (TEM), Fourier Transform Infra-Red (FT-IR), Ultra Violet reflectance analysis (UV), Scanning Electron Microscope (SEM), Energy dispersive X-ray Spectroscopy (EDX), Photoluminescence (PL) Spectroscopy and Raman spectroscopy. The results proved that the mother carbon nanotubes have a high surface area and total pore volume and are found to be 247m2/g and 0.569 cm3/g, respectively, and its surface area decreased upon loading the metal nanoparticles. Pore size distribution curve (PSD) exhibited a wide mesopore centered at 30 nm. TEM results revealed that Cu and Zn metals are randomly distributed and located at the nanotube's surface and the tips of the tube via the tip-growth mechanism. It is obviously seen that the Zn/CNTs have a homogenously uniform diameter as compared to the neat CNTs. The nanocomposites' photodegradation% rank was Zn/CNT > Cu/CNT > Cu-Zn/CNT, which related mainly to the chemical composition of Zn/CNT composite. Zn/CNT composite showed the highest degradation efficiency among the prepared composites, which achieved 97.7% after 70 minutes under visible light irradiation. The mechanism of the photocatalytic degradation of congo red dye under visible light irradiation was discussed.
composites materials
Congo Red Dye
Nano-materials and Photocatalytic degradation
2021
03
01
1481
1494
https://ejchem.journals.ekb.eg/article_126523_27dc898461224bcd70aa4c49bc5820ca.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Studies of Synthesized Nonionic Gemini Surfactant Based On Sulfonamide Moiety as Flow Enhancing Additive of Waxy Crude Oil
aziza
S. El-Tabei
Enas
Arafa
taisir
Khidr
One of the most severe and long term issues in the petroleum industry is paraffin wax deposit of crude oil at low temperatures.The use of pour point depressants (PPD) has proven to be an effective method for preventing wax deposition.In this research, the synthesized nonionic gemini surfactant (NGS) is utilized as a PPD additive.The surface parameters of the NGS were assessed as the interfacial tension (IFT). The effectiveness of this additive as a PPD on the cold-flow properties of crude oil was investigated.Additionally, the commercial additive (CA) only and combined with NGS via varying ratio was properly evaluated as good PPD.The pour point (PP) measurements exhibit a significant decrease in the PP temperature, based on the particular ratio of NGS to CA and the different concentrations of additives in the crude oil sample.The additive (1mol NGS: 1mol CA) lowers pour point crude oil sample to a significant degree.At various temperatures below, high and equal to PP temperature, the shear rate-shear stress and shear rate- viscosity were estimated.The wax morphology has been observed to be substantially changed to fine, scattered crystals of a compact shape by the photomicrographic examination.
Key words:Gemini nonionic surfactant
Pour Point
wax modification
Surface properties
and waxy crudeoil
2021
03
01
1495
1502
https://ejchem.journals.ekb.eg/article_131522_883db24c6092ae7bad6c468a734fd87b.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Convenient Synthesis Of New Indeno[1,2-b]Pyridine Derivatives For Antimicrobial And Antioxidant Evaluation
Eman
Kotb
Hanan
Soliman
Eman
Hassan
Asmaa
Negm El-Dein
A new set of 1H-indenopyrdine-based derivatives were synthesized using the compound 4-(4-hydroxy-3-methoxyphenyl)-2-oxo-2,5-dihydro-1H-indeno[1,2-b]pyridine-3-carbonitrile (1) as the key starting compound. The molecular structures of the new derivatives were identified using various spectroscopic techniques and elemental analysis. All the new analogues were screened as antimicrobial against different strains of +ve gm, -ve gm bacteria and the opportunistic pathogenic yeast C. albicans. Some of the new indenopyrdines exhibited moderate antimicrobial activity comparing to gentamicin as a standard drug. On the reverse, the free radical scavenging activity of the new compounds using DPPH assay protocol revealed that most of the compounds were potent antioxidant agents while comparing to ascorbic acid as a positive antioxidant control.
1H- indenopyrdine
Schiff’s bases
Thiazolidinone ring
antimicrobial activity
antioxidant
2021
03
01
1503
1515
https://ejchem.journals.ekb.eg/article_128415_06471bd6bad47fa7afff69345581cd71.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Novel Melatonin Derivatives: Synthesis, Anticancer Evaluations and Molecular-Docking Study
Mahmoud
Alsayed
Dina
El-Kady
mohamed
tantawy
Mervat
AbdElhalim
Samia
Elazabawy
Amira
Abdallah
Gamal
Elmegeed
Many studies mentioned that Melatonin considers an anti-cancer agent. So in this study, a lot of novel Melatonin derivatives incorporated different heterocyclic ring systems such as triazole, thiadiazole, tetrazole, thiazole, thiophene and pyrazole were synthesized. The synthesized compounds 5, 6, 8, 11, 15, 16 and 19 were evaluated as anti-cancer by using two human cancer cell lines, Breast cancer (MCF7) and colon cancer (HCT-116). The synthesized compounds showed a gradual decrease in the cell viability of the two cell lines. We also observed that compound 16 was the lowest IC50 and the highest cytotoxic effects against the two cancer cell lines. Furthermore, the molecular-docking study was employed to determine the possible mode of action of the synthesized compounds against proteins (CDK2 and P53-MDM2) which, were considered to be potential proteins involved in the pathogenesis of cancer. We observed that compound 16 was the best-docked ligand against the targeted proteins, as it displayed the lowest binding energies, critical hydrogen bonds, and hydrophobic interactions compared to other tested compounds.
Anticancer
azole
azine
THIOPHENE
Melatonin
molecular-docking
2021
03
01
1517
1533
https://ejchem.journals.ekb.eg/article_131523_6406fae2358843c9b3c1a1b717fa33e9.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Investigation of the Oxidative Degradation Pathway of Amidoximes by LC/MS/MS
Ebtihal
Samir
Mamdouh
Mamdouh
Sayed
M Derayea
The oxidative degradation pathway for a newly prepared amidoxime prodrug has been studied using LC/MS/MS. The amidoxime was subjected to oxidation with K3Fe(CN)6/NaOH for different time periods and at different temperatures. The chromatographic separation was performed on RP amide column and 0.1% aqueous formic acid; acetonitrile containing 0.1% formic acid (50:50 v/v) as a mobile phase. The elution in Ultra-performance liquid chromatography (UPLC) was carried out in the isocratic mode. The normal LC/MS/MS showed that the cleavage occurs through amidoxime ester. At room temperature, no important oxidation products were obtained. However, upon heating the parent amidoxime was disappeared with the concomitant appearance of a new compound which is the most stable peak (base peak) at m/z = 333.80. The formed degradation product was suggested to be the disodium salt of benzaldoxime peroxide. These results give indication about the mechanism of release of nitric oxide from amidoxime and ensure that amidoximes are important nitric oxide donors.
Amidoximes
Potassium Ferricyanide
Oxidative Degradation, LC/MS/MS
2021
03
01
1535
1540
https://ejchem.journals.ekb.eg/article_130403_4202eff4372d0ba5b2cbfd265fea8d9a.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
A New Insight into Pleiogynium timorense Leaves: A Focus on The Anticancer and Antimicrobial Potentials
Gehan Fawzy
Abdel Raoof
Ataa
Said
Shaymaa
Ismail
Amira
El-anssary
The current study focused on the anticancer and antimicrobial potentials of the ethyl acetate extract of Pleiogynium timorense leaves and the characterization of its phytoconstituents. Ethyl acetate extract of pleiogynium timorense leaves showed a potent cytotoxic activity against ovarian cancer cell line (SKOV-3) with IC50 of (7.13 μg/mL) and a moderate activity against liver cancer cell line (HEPG-2) with IC50 =20.42 μg/mL , while it possessed a weak activity against Prostate cancer cell line (PC-3) (IC50 >100 μg/mL). In addition, the extract exhibited reasonable antibacterial activity against Staphylococcus aureus, Bacillus cereus, and Escherichia coli with MIC values of (200, 500 and 500 mg/ml), respectively without the detection of any activity against Salmonella typhimurium, Candida albicans and Aspergillus brasiliensis. The phytochemical study revealed the identification of eleven polyphenolic compounds representing 80.8 % of the total area; the major compounds were chlorogenic acid (40.8 %), gallic acid (11.1%), catechin (8.2%) and taxifolin (7.6 %). Moreover, gallic acid, kaempeferol and catechin were isolated and identified for the first time from the ethyl acetate extract. In addition, the plant extract is found to be rich in natural pigments (total carotenoids = 864.64 g/100g). In conclusion, the current study revealed that ethyl acetate extract of Pleiogynium timorense leaves is rich with polyphenolic compounds, which play a vital role in the plant bioactivities.
Pleiogynium timorense leaves
cytotoxic
Antimicrobial
phytoconstituents
2021
03
01
1541
1551
https://ejchem.journals.ekb.eg/article_130404_44cf9595ecdc5a38cac3c9fde5932ec2.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Effect of Granite Weathered Granules Additives as Aggregates In Cement Concrete
Ali.I.M.
Ismail
Mohamed
Elmaghraby
Nahla
Abd El Ghaffar
Granitic weathering products were obtained from South Sinai. These aggregates were assessed to be used in the manufacturing of cement concrete. Chemical and mineralogical compositions and physical parameters of the selected samples were carried out. The composition of the main phase is quartz, albite, and microcline, while river sand shows only quartz as one phase. Four batches were designed with two different grain size divisions between the fine to medium granules. Two batches were designed with aggregates of granite weathering products only for all sizes. The other two batches were designed with coarse and medium granite aggregates and a fine of river sand. Some technological characteristics of the four batches in terms of bulk density, expansion, and compressive strength were detected. It is deduced that the replacement of the fine granite weathering products fraction with the river sand in two ratios (10 & 20%) yields higher amounts of the technological properties. The maximum compressive strength results recorded are 101.53% and 180.92%, in the batch nos. 4 and 3, respectively. The batch contains 20% of the river sand, fine fraction is denser and higher expansion and crushing strength values. SEM and EDX of the batches nos. 2 and 3 support the technological properties and the phase composition of the main component of granite and river sand granules as well as the composition of the main oxides of the OPC common in the market and elucidated that the river-sand as fine granules has better technological characteristics than the granite fine granules.
Granitic- weathering
Concrete. Technological properties
2021
03
01
1553
1562
https://ejchem.journals.ekb.eg/article_125550_bb4d719391e9d83089a5a5e614ab1a12.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Formulation, Development and Physicochemical Characterization of Diclofenac Topical Emulgel
Amrita
Nayak
Sudip
Mandal
Mohmmed
Ramadan
Santosh
Rath
Emulgel is one of the convenient and promising topical drug delivery approaches especially for the hydrophobic drugs. The purpose of the study was to prepare emulgel of diclofenac sodium using polymers namely Carbopol-934, hydroxypropyl methyl cellulose and sodium carboxy methyl cellulose and studied for their drug release from the gel formulations. The 1% Carbopol-934 formulated gel was found highest drug content (101.72%) than the other formulations. The pH of the formulations ranged from 6.8 to 7.2 and viscosity is from 36,000 to 51,000 cps. Extrudability of carbopol and HPMC gels were excellent than the SodiumCMC gel. In vitro drug release was observed highest (64.91%) for the formulation A2 (1% Carbopol-934) and was improved further on the addition of DMSO as a permeation enhancer. In the same time, 1.0% carbopol-940 also showed a similar release pattern, but the release was lesser (51.47%) and the release of HPMC and sodium CMC gels was much lesser. The study revealed that formulation A2 with 1% Carbopol-934 was observed to be the best formulation having good in vitro release profile, stability and bioavailability among all prepared formulations. Hence, the study brought to a close idea that the emulgel A2 was a successful outcome as a topical anti-inflammatory and analgesic formulation among all.
Emulgel
Topical drug delivery
diclofenac sodium
nonsteroidal anti-inflammatory drug
Carbopol-934
2021
03
01
1563
1573
https://ejchem.journals.ekb.eg/article_147889_deee46aa93c36e411d2d20d3eee4d2aa.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Synthesis, Biological Evaluation and In Silico Investigation of Novel Functionalized Imidazole-Based KDM6 Inhibitors
Amr
El-Araby
Omar
Qassem
Ezzat
El-Sawy
Eman
El-Razaz
Khaled
Abouzid
Rabah
Serya
Epigenetic markers of the cellular genome are major controllers of the transcriptional level of various genes in physiological and pathological states. These markers are written and erased by epigenetic factors which have been recently studied as potential therapeutic targets of various disease states. Histone lysine demethylases are an example of these epigenetic factors. The subfamily number 6 of these enzymes (KDM6) are an understudied group of histone demethylases which have been recently connected to cancers and inflammation. In this work, we conducted a rational and computer-aided approach to design and synthesize KDM6 inhibitors. The designed inhibitors are imidazole-based and are functionalized with variable metal-chelating group to be able to chelate the active site ferrous ion. One of the synthesized compounds, compound 6, was able to inhibit KDM6-expressing cancer cell lines by more than 50%. Molecular docking studies suggest that this compound is able to achieve important active site interactions and coordinate the active site metal through a tridentate interaction. Furthermore a correlation was established between the structural features and CLogP of the tested compounds and their activity. These results represent a promising starting point for the future development of novel KDM6 inhibitors with higher potency.
KDM6
JMJD3
GSK-J1
Cervical Cancer
Prostate Cancer
NSCLC
docking
2021
03
01
1575
1582
https://ejchem.journals.ekb.eg/article_126734_65c2fa2bfbb1412a73be08c71b72aff1.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Validated HPLC Method for Quantitative Analysis of Gallic Acid and Rutin in Leaves of Moringa Oleifera Grown in Egypt
Sabrien
Mohamed
Ahmed
Youssef
Magda
Issa
Hemat
Abdel Salam
Aida
El-Ansary
Moringa oleifera is one of miracle tree and great interested medicinal plant which belongs to Moringaceae. It is widely used as a nutritive herb and possesses valuable pharmacological activities. In our study a rapid, sensitive and accurate HPLC method for qualitative and quantitative determination of gallic acid and rutin in two different solvent methanol and ethanol, extracts of Moringa oleifera leaves cultivated in Egypt was investigated. The separation was performed and validated by isocratic method utilizing C18 column with a mobile phase 10% (v/v) acetonitrile and 1.0% aqueous acetic acid mixture for gallic acid and 60% (v/v) methanol and 1.0% aqueous acetic acid mixture for rutin. Those bioactive components, gallic acid and rutin, were detected at 280 and 335 nm, respectively. The calibration graph was found to be linear in the concentration ranges 5.0-40.0 and 5.0-60.0 µg/mL for gallic acid and rutin, respectively. The higher concentrations of gallic acid were observed in the 50% methanolic and ethanolic extracts, while the higher concentrations of rutin were observed in the 100% methanolic and ethanolic extracts. Moreover, a successfully spectrophotometric quantification of the total phenolics and flavonoids content in the plant extract was achieved, where the equivalent amount to gallic acid in methanolic and ethanolic extracts and the equivalent amount to rutin in methanolic and ethanolic extracts were calculated.
Moringa oleifera
Gallic acid
Rutin
HPLC
2021
03
01
1583
1591
https://ejchem.journals.ekb.eg/article_123806_96dd999898d9e37b797fb082c8e50b3e.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Adsorption Studies of Cationic Dye on Raw And Modified Sugarcane Bagasse from Aqueous Solutions: Kinetic and Isotherm Aspects
Sara
Abd Elhafez
Azza
El-Maghraby
Nahla
Taha
Adsorbent materials for industrial and environmental applications are the goal of seeking research under active investigation now. Activated carbons could be obtained from the organic material after been chemically or physically treated. In Egypt, Sugarcane bagasse could be considered one of the agricultural wastes that frequently produced. In this study, the low-cost adsorbent was prepared from raw Bagasse. The batch experiment was set up to determine the effect of using the agriculture waste (sugarcane bagasse) without any modification and activated it chemically and physically on methylene blue removal. The influence of adsorbent amount, agitation rate, and temperature on the dye removal were studied. The result shows that the percentage of dye removal reached up to %99.6 when the initial dye concentration was 15 ppm, and the amount of sorbent (chemically activated) was 0.3 g at room temperature. The adsorption kinetics and isotherms for the removal of methylene blue were represented with different models. It was detected that Langmuir and Freundlich's equations have the R2 value closed to unity, and the maximum adsorption calculated capacity was 2.2 mg/g when the initial dye concentration was 15 ppm. Furthermore, pseudo-first-order and pseudo-second-order were fitted to examine the adsorption kinetic, and a pseudo-second-order calculated the highest adsorption rate for the raw bagasse (0.59446 g/mg.min).
Cationic dye
methylene blue
Sugarcane bagasse
kinetic
and Isotherm
2021
03
01
1593
1600
https://ejchem.journals.ekb.eg/article_129000_48f5110045971886ab828e45c0163814.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Facile validated HPLC method using photodiode array detector for the combined analysis of etodolac and 5-FU in bulk and tablet dosage form
Honey
Goel
Richu
Singla
Rakesh
Chawla
Ujjwal
Sahoo
Ashok
Tiwary
Vivek
RanjanSinha
The aim of the investigation was to develop and validate a reversed-phase high-pressure liquid chromatography (RP-HPLC) method for the simultaneous estimation of etodolac and 5-FU in bulk and coated tablet dosage form. The method was validated in terms of linearity, precision, accuracy, and specificity, LOD, and LOQ according to ICH guidelines. The standard instrument parameters were optimized using C18 reverse phase Inertsil® ODS (250 × 4.6 mm, 5µ particle size) column with system equipped with photodiode array (PDA) detector. An optimized ratio of mobile phase in RP-HPLC under low pressure gradient mode comprising of 60:40 % v/v of acetonitrile and di-potassium hydrogen phosphate buffer (pH 6.4; 25 mM), provided sharp peaks (having adequate molar absorptivity at λmax of 280 nm) with short retention time of 4.3+/-0.2 and 11.5+/-0.3 min for 5-FU and etodolac, respectively. Results indicated the method was linear, precise, accurate, rugged and robust with RSD values <2%. The percentage recoveries of both the drugs were within the limits of 90-110% at various spiked concentrations. The proposed method was found to be highly effective and could be successfully employed for the quantification of 5-FU and ETD in bulk drug and tablet formulations for routine analysis.
RP-HPLC
5-FU
ETD
validation
Tablets
photodiode array (PDA)
2021
03
01
1601
1614
https://ejchem.journals.ekb.eg/article_128405_0f4a4d6e3aa55e9c3d9f9b4135805604.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Biofilm Formation by Clinical Acinetobacter baumannii strains and its effect on antibiotic resistance
Abdulaziz Abdullah Othman
Almosa
Ali A.
Al-Salamah
Dina A.
Maany
Mostafa
El-Abd
Abdelnasser S.S.
Ibrahim
Acinetobacter baumannii is one of the most important nosocomial, multidrug resistant pathogens. The most important virulence factor is its ability to form biofilms. Microtiter-plate method was used to detect the ability of twenty A. baumannii clinical strains to form biofilm in polystyrene wells. Biofilm formation was assessed by staining with a crystal violet solution 0.1% then elution by an ethanol-acetone mixture (80:20) and O.D measurement. In general, among the twenty isolates, 2 isolates were strong biofilm formers, 13 were medium and 5 were weak. It is worthy to mention that the strong biofilm forming strains were those isolated from tracheal aspirates and wound swabs. When examining environmental factors' effects on biofilm formation, results revealed that biofilm formation was enhanced in the presence of lactose as a carbon additive. Production of biofilm was maximum at pH 6 and 7.4 as indicated from O.D values. Biofilm formation was better at all temperatures with a slight increase at 40oC and was maximum after 72h. The effect of addition of serum on biofilm formation varies among the isolated samples giving rise to high O.D values in sample 2 and 4. Non-biofilm producing mutant generated by 70% CV treatment of strain no. 1 was tested and found to be as antibiotic resistant as the wild type strains indicating the contribution of other factors in addition to biofilm to resist antibiotics.
Acinetobacter baumannii
Nosocomial infection
Biofilm
multidrug resistant pathogens
Mutagenesis
2021
03
01
1615
1625
https://ejchem.journals.ekb.eg/article_128410_8fcfa261f0a2f0b60f9c5966ae63cea5.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Nano-organometallic complexes as therapeutic platforms against breast cancer cell lines; (in vitro study)
Abdu
El Tabl
Moshira
Abdel Wahed
Marwa
El Assaly
Ahmad
Ashour
Improvements have been made to chemotherapies because drugs are still not reaching the tumor site at effective doses and are often associated with high systemic toxicities and poor pharmacokinetics. The nanotechnology allows more effective and less toxic chemotherapy. It has been shown that, many anticancer drugs are not able to penetrate more than 40-50 mm (equivalent to combined diameter of 3-5 cells from the vasculature). These defects lead to incomplete tumor response, multiple drug resistance and therapeutic failure. The best way to increase the efficacy and reduce the toxicity of a cancer drug is to direct the drug to its target and maintain its concentration at the site for a sufficient time for therapeutic action to take effect. Cu(II), Zn(II) and mixed Cu(II) /Zn(II) nano complexes center on opportunities for improving this process. Nano complexes of bioactive ligands had been prepared and spectroscopically characterized. The electron microscopic data confirmed the nanoform of these complexes in the range (12.2 – 85.0 nm). Invitro antitumor activity of the complexes had been studied against breast cancer cell lines and the IC50 values were detected to show that the order of the cytotoxic effect was complex (4) (Cu(II) acetate) > complex (1) (Cu(II) chloride) > complex (2) (mixed Cu(II)/Zn(II) acetate) > complex (3), (Zn(II) acetate). The invivo cytotoxicity of the complexes showed that, the complexes have no side effects after six weeks was confirmed by clinical and histopathological studies. The results augur well for breast cancer treatment.
Bioactive ligands
nano complexes
Spectral studies
invitro and invivo cytotoxicity
2021
03
01
1627
1637
https://ejchem.journals.ekb.eg/article_126736_0fffbe49502f41a09e58731edfc3d390.pdf
Egyptian Journal of Chemistry
Egypt. J. Chem.
0449-2285
0449-2285
2021
64
3
Determination of 3-MCPD in Some Edible Oils using GC-MS/MS
Rania
Almoselhy
Mounir
Eid
Walid
Abd El-Baset
AlaaEldean
Aboelhassan
The presence of 3-monochloropropanediol (3-MCPD) in edible oils has been widely reported with its potential health risks. The aim of this study was to apply optimized recent updated and validated enhanced swift analytical indirect method for determining 3-MCPD in consumed edible oils (palm, palm olein, extra virgin olive, corn, sunflower, soybean, olive pomace) and blend of 5% sunflower oil with extra virgin olive oil, using selective and sensitive gas chromatography tandem triple quadrupole mass spectrometry (GC-MS/MS) employing deuterated 3-MCPD (3-MCPD-d5) as internal standard (IS) during the entire analytical procedure to obtain precise and accurate results. The occurrence and variation of 3-MCPD contents among the studied oils were found in different levels ranged from 93.1 µg/kg to 5634.1 µg/kg oil samples, with maximum value assigned for palm oil (5634.1 µg/kg) followed by palm olein (5576.8 µg/kg), corn oil (2447 µg/kg), sunflower oil (1817.3 µg/kg), soybean oil (1486.1 µg/kg), olive pomace oil (572.5 µg/kg), blend of 5% sunflower oil with extra virgin olive oil (210 µg/kg) and extra virgin olive oil (93.1 µg/kg). Palm, palm olein, corn, sunflower and soybean oils were found out of the limits recommended by the Commission Regulation (EU) 2020/1322, whereas, extra virgin olive oil, olive pomace oil and blend of 5% sunflower oil with extra virgin olive oil were in compliance and within the limits recommended by EU. Moreover, 3-MCPD content could be used as a good tool for authenticity and quality of genuine extra virgin olive oil.
Edible oils
3-Monochloropropanediol (3-MCPD)
GC-MS/MS
Food contaminants
2021
03
01
1639
1652
https://ejchem.journals.ekb.eg/article_153433_4c3a4aa60733221fbbb2d5cd9765860a.pdf